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Standard Amblyopia Therapy in Adult Amblyopes

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ClinicalTrials.gov Identifier: NCT03341780
Recruitment Status : Completed
First Posted : November 14, 2017
Last Update Posted : November 17, 2017
Sponsor:
Collaborator:
Allergan
Information provided by (Responsible Party):
Southern California College of Optometry

Brief Summary:
Amblyopia is characterized by a reduction in visual acuity, contrast sensitivity, and binocular visual functions. The two main causes of amblyopia are anisometropia and strabismus which alter the synaptic connections between neurons along the visual pathway. Current treatment for amblyopia has indicated that the younger the amblyope, the greater the effect of treatment. The purpose of this study is to determine if standard amblyopia treatment improved visual acuity in adult amblyopes.

Condition or disease Intervention/treatment
Amblyopia Procedure: amblyopia therapy

  Show Detailed Description

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Study Type : Observational
Actual Enrollment : 9 participants
Observational Model: Cohort
Time Perspective: Prospective
Official Title: Standard Amblyopia Therapy in Adult Amblyopes
Actual Study Start Date : December 16, 2014
Actual Primary Completion Date : October 24, 2016
Actual Study Completion Date : October 24, 2016

Resource links provided by the National Library of Medicine

MedlinePlus related topics: Amblyopia


Intervention Details:
  • Procedure: amblyopia therapy
    Any of the following amblyopia training activities may be employed during patching: board games, card games, coloring in O's, comic books, craft projects, crossword puzzles, dot-to-dot patterns, drawing, hammering nails, jacks, jigsaw puzzles, lego and other blocks, marbles, mazes, peg-board activities, perceptual materials, pickup sticks, reading, sewing, shooting games, stringing beads, throwing or hitting games, tracing, and video or computer games.


Primary Outcome Measures :
  1. visual acuity [ Time Frame: 24 weeks ]
    LogMAR acuity will be measured with the eETDRS chart



Information from the National Library of Medicine

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Ages Eligible for Study:   18 Years and older   (Adult, Older Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population
Subjects will be recruited from the College community and University Eye Clinic. An announcement will be made to the College community and volunteers accepted.
Criteria

Inclusion Criteria:

  • Amblyopic patients with acuities between 20/40 (0.30 logMAR) and 20/400 (1.30 logMAR).
  • All subjects will be over the age of 18.
  • Prior amblyopia therapy is not an exclusion criteria.
  • Subjects will be recruited from the College community and University Eye Clinic.

Exclusion Criteria:

  • A significant cataract that affects vision.
  • Glaucoma, diabetes, uncontrolled high blood pressure.
  • Other ocular or systemic diseases that will affect visual acuity.
  • The inability to give informed consent.

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT03341780


Sponsors and Collaborators
Southern California College of Optometry
Allergan
Investigators
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Principal Investigator: William Ridder, OD, PhD Southern California College of Optometry

Publications:
Michaels DD. Visual optics and refraction: a clinical approach. St Louis, MO: C.V. Mosby Co.; 1980.

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Responsible Party: Southern California College of Optometry
ClinicalTrials.gov Identifier: NCT03341780     History of Changes
Other Study ID Numbers: SoutherCCO
First Posted: November 14, 2017    Key Record Dates
Last Update Posted: November 17, 2017
Last Verified: November 2017
Individual Participant Data (IPD) Sharing Statement:
Plan to Share IPD: Undecided

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Studies a U.S. FDA-regulated Drug Product: No
Studies a U.S. FDA-regulated Device Product: No
Additional relevant MeSH terms:
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Amblyopia
Brain Diseases
Central Nervous System Diseases
Nervous System Diseases
Vision Disorders
Sensation Disorders
Neurologic Manifestations
Eye Diseases
Signs and Symptoms