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Outcomes of Acute Kidney Injury in Critically Ill Patients

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ClinicalTrials.gov Identifier: NCT03338127
Recruitment Status : Not yet recruiting
First Posted : November 9, 2017
Last Update Posted : November 13, 2017
Sponsor:
Information provided by (Responsible Party):
Alaa H Fahmy, Assiut University

Brief Summary:
this study to evaluate the frequency of acute kidney injury in critically ill patients in intensive care units.

Condition or disease Intervention/treatment
Acute Kidney Injury Diagnostic Test: renal function test

Detailed Description:

Acute kidney injury (AKI) affects approximately 20% of hospitalized patients and up to 67% of those admitted to an intensive care unit (ICU), making it among the most common organ dysfunctions among the critically ill . Depending on severity, Acute kidney injury (AKI) contributes to short-perimortality rates between 40% and 70% , and survivors are at increased risk for chronic kidney disease (CKD) and late death.

The diagnosis of Acute kidney injury (AKI) is only considered after achieving an adequate status of hydration and after excluding urinary obstruction; Acute kidney injury (AKI) is defined by the sudden decrease (in 48 h) of renal function, defined by an increase in absolute serum creatinine of at least (0.3 mg/dL) or by a percentage increase in serum creatinine ≥50% (1.5× baseline value), or by a decrease in the urinary output (documented oliguria <0.5 mL/kg/h for more than 6hours).

The purpose of this study was to benchmark the outcomes of acute kidney injury in a critically ill surgical patients.We hypothesized that renal dysfunction in this population is common and is associated with a significantly higher burden of morbidity, mortality, and resource utilization


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Study Type : Observational
Estimated Enrollment : 40 participants
Observational Model: Case-Only
Time Perspective: Retrospective
Official Title: Outcomes of Acute Kidney Injury in Critically Ill Patients in Luxor International Hospital
Estimated Study Start Date : December 1, 2017
Estimated Primary Completion Date : June 30, 2018
Estimated Study Completion Date : June 30, 2018

Resource links provided by the National Library of Medicine

MedlinePlus related topics: Kidney Tests

Group/Cohort Intervention/treatment
Participants
all patients recruited in the trial will be investigated for renal function test
Diagnostic Test: renal function test
2 ml blood sample to be investigated for renal function test




Primary Outcome Measures :
  1. Acute kidney injury in critically ill patients [ Time Frame: 10 days ]
    To evaluate the frequency of acute kidney injury in critically ill patients admitted in intensive care units.



Information from the National Library of Medicine

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Ages Eligible for Study:   Child, Adult, Older Adult
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Probability Sample
Study Population
patient willl be recruited from critical care units in Luxor international hospital
Criteria

Inclusion Criteria:

• All patient with acute kidney injury in critical care units in Luxor international hospital

Exclusion Criteria:

  • Patients on chronic dialysis
  • Previous acute kidney injury
  • Nephrectomy
  • Organ transplant
  • Chronic kidney disease

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT03338127


Contacts
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Contact: Alaa H Fahmy 00201118929161 alaaheshmat90@gmail.com

Sponsors and Collaborators
Alaa H Fahmy
Investigators
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Study Director: Ahmed M Aly, professor professor of internal medicine

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Responsible Party: Alaa H Fahmy, Principal Investigator, Assiut University
ClinicalTrials.gov Identifier: NCT03338127     History of Changes
Other Study ID Numbers: AssiutU AHFahmy
First Posted: November 9, 2017    Key Record Dates
Last Update Posted: November 13, 2017
Last Verified: November 2017
Individual Participant Data (IPD) Sharing Statement:
Plan to Share IPD: Undecided

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Studies a U.S. FDA-regulated Drug Product: No
Studies a U.S. FDA-regulated Device Product: No

Additional relevant MeSH terms:
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Wounds and Injuries
Critical Illness
Acute Kidney Injury
Disease Attributes
Pathologic Processes
Renal Insufficiency
Kidney Diseases
Urologic Diseases