MR Guided tDCS in Alzheimer's Disease
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|ClinicalTrials.gov Identifier: NCT03325205|
Recruitment Status : Recruiting
First Posted : October 30, 2017
Last Update Posted : October 30, 2017
|Condition or disease||Intervention/treatment||Phase|
|Alzheimer's Disease||Other: Anodal tDCS Other: Sham tDCS||Not Applicable|
|Study Type :||Interventional (Clinical Trial)|
|Estimated Enrollment :||30 participants|
|Intervention Model:||Parallel Assignment|
|Masking:||Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)|
|Official Title:||MR Guided tDCS: The Effect of Repeated Transcranial Direct Current Stimulation on Cognitive Functioning in Alzheimer's Disease|
|Actual Study Start Date :||August 22, 2017|
|Estimated Primary Completion Date :||June 30, 2019|
|Estimated Study Completion Date :||December 30, 2020|
Experimental: Active tDCS
Participants receive anodal tDCS over DLPFC. Each sessions lasts for 20 minutes, with a total of 15 stimulations: 6 acute sessions, 9 maintenance sessions.
Other: Anodal tDCS
Anodal Transcranial direct current stimulation (tDCS) is a non- invasive brain stimulation technique. Low intensity current (1-2 mA) is induced to increase excitability, stimulate plasticity and enhance cognitive functions.
Sham Comparator: Sham tDCS
Participants receive sham tDCS over DLPFC. Each sessions lasts for 20 minutes, with a total of 15 stimulations: 6 acute sessions, 9 maintenance sessions.
Other: Sham tDCS
The electrodes are placed over the same areas as in the anodal tDCS condition. Participants will receive sham tDCS instead of anodal tDCS
- Performance on Neuropsychological tests [ Time Frame: 4 months ]Compare scores before and after tDCS stimulation
- Hippocampal volume [ Time Frame: 4 months ]Compare performance on neuropsychological tests to hippocampal volume. Here we are looking at correlations between hippocampal thickness, performance on neuropsychological tests and effect of tDCS.
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT03325205
|Contact: Ingrid D. Rasmussen, Cand.firstname.lastname@example.org|
|Department of Psychology, University of Northern Norway||Recruiting|
|Contact: Per M. Aslaksen, Professor 004777649234 email@example.com|
|Contact: Ingrid D. Rasmussen, Cand.psych. 004777620809 firstname.lastname@example.org|
|Principal Investigator:||Per M Aslaksen, Professor||University of Tromso|