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Mesenteric Panniculitis : Review of Consecutive Abdominal MDCT Examinations With a Matched-pair Analysis (MP - Cancer)

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ClinicalTrials.gov Identifier: NCT03316001
Recruitment Status : Completed
First Posted : October 20, 2017
Last Update Posted : October 20, 2017
Sponsor:
Information provided by (Responsible Party):
CHU de Reims

Brief Summary:
Mesenteric panniculitis is a benign inflammatory condition that involves the adipose tissue of the intestinal mesentery. Clinical manifestations are uncommon, non specific and atypical. Mesenteric panniculitis is thus most often an incidental finding during an investigation for other reason, mostly on computed tomography scans. The rate of malignancy in patients with mesenteric panniculitis, especially urogenital and gastrointestinal adenocarcinomas or lymphomas, has been reported to be as high, thus suggesting that there may be a relationship between mesenteric panniculitis and progression of an underlying malignancy or the risk of a future malignancy.

Condition or disease Intervention/treatment
Mesenteric Panniculitis Other: Review of multidetector row computed tomography scans

Detailed Description:

The aim was:

to estimate the prevalence of mesenteric panniculitis. to study relationship between mesenteric panniculitis and malignancy. to investigate the 5-year outcome of patients with mesenteric panniculitis for the development of malignancy.


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Study Type : Observational
Actual Enrollment : 288 participants
Observational Model: Case-Control
Time Perspective: Retrospective
Official Title: Mesenteric Panniculitis : Review of Consecutive Abdominal MDCT Examinations With a Matched-pair Analysis
Actual Study Start Date : November 2014
Actual Primary Completion Date : March 2015
Actual Study Completion Date : July 2015

Resource links provided by the National Library of Medicine


Group/Cohort Intervention/treatment
cases
patients with a CT scan from January to August 2008 for which mesenteric panniculitis was diagnosed
Other: Review of multidetector row computed tomography scans
multidetector row computed tomography scans

controls
patients with a CT scan from January to August 2008 for which mesenteric panniculitis wasn't diagnosed and matched by gender and age with "cases" patients
Other: Review of multidetector row computed tomography scans
multidetector row computed tomography scans




Primary Outcome Measures :
  1. mesenteric panniculitis [ Time Frame: Day 0 ]

    mesenteric panniculitis is identified on the basis on the presence of three of the following 5 signs on CT scan:

    • higher attenuation of the fat of the root of the small bowel mesentery,
    • a pseudo mass smoothly displacing neighboring structures with a hyperdense pseudocapsule surrounding the mesenteric fat,
    • lymph nodes within the fatty pseudo mass and
    • a hypodense halo around the nodes and the blood vessels



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Ages Eligible for Study:   18 Years and older   (Adult, Older Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population
Patients with a CT scan from January to August 2008 for which mesenteric panniculitis was diagnosed
Criteria

inclusion criteria:

  • Patients with a CT scan from January to August 2008
  • Patients with diagnosis of mesenteric panniculitis on CT scan

exclusion criteria:

  • Patients with disease that may cause mesenteric infiltration

Publications:
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Responsible Party: CHU de Reims
ClinicalTrials.gov Identifier: NCT03316001     History of Changes
Other Study ID Numbers: 2016Ao002
First Posted: October 20, 2017    Key Record Dates
Last Update Posted: October 20, 2017
Last Verified: October 2017

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Studies a U.S. FDA-regulated Drug Product: No
Studies a U.S. FDA-regulated Device Product: No
Additional relevant MeSH terms:
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Panniculitis, Peritoneal
Panniculitis
Connective Tissue Diseases
Skin Diseases
Peritoneal Diseases
Digestive System Diseases