Outcomes of Surgical Correction of Penile Curvature in Adult
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|ClinicalTrials.gov Identifier: NCT03313986|
Recruitment Status : Not yet recruiting
First Posted : October 19, 2017
Last Update Posted : October 19, 2017
Penile curvature in adults is divided into two main categories the first is congenital penile curvature with orthotopic meatus and the other is acquired curvature which its common causes are Peyronie's disease (PD) and previous penile surgery as for hypospadias repair.The congenital penile curvatures (CPC) which not associated with urethral malformation is a relatively uncommon condition that may present in late adolescent or early adult life. The incidence is estimated to be 0.6 % but the incidence of clinically significant CPC is much lower, as the degree of curvature and sexual dysfunction varies widely Penile curvature may lead to inability for sexual intercourse. These cases require treatment. Acquired penile curvature its most common cause is Peyronie's disease. Peyronie's disease is a fibrotic disorder of the tunica albuginea of the corpora cavernosa that is clinically defined by the presence of a palpable, inelastic tunical plaque. PD is relatively common and affects up to 20.3% of adult men to some degree.
Surgery is gold-standard for treatment of curvature in stable PD. Surgical therapy is subdivided into three main procedures: (1) plication techniques (Penile shortening procedures), (2) grafting procedures with partial plaque excision or incision followed by defect closure with various grafts, and (3) correction of deviation with simultaneous penile prosthesis implantation in patients with ED not responding to medical therapy.
In this study results of different surgical techniques in management of penile curvature will be compared.
|Condition or disease|
|Complication of Surgical Procedure|
Show Detailed Description
|Study Type :||Observational|
|Estimated Enrollment :||50 participants|
|Official Title:||Outcomes of Surgical Correction of Penile Curvature in Adult|
|Anticipated Study Start Date :||November 1, 2017|
|Estimated Primary Completion Date :||November 1, 2020|
|Estimated Study Completion Date :||December 1, 2020|
- Correcting the curvature. [ Time Frame: 3 months postoperative ]Measure of any residual curvature present by using the protractor.
- Preserving erectile function and hardness. [ Time Frame: 4 months ]to show any affection of erectile function by using Interarnational index of Erectile dysfunction questionnaire.
- Preserving penile length. [ Time Frame: 3 months ]to measure penile length postoperative and compare to the preoperative length
- Penile sensation. [ Time Frame: 3 months ]To show any affection of penile sensation postoperative
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT03313986
|Contact: Mohamed Elgendy, email@example.com|