the Effect of Three Different Analgesic Techniques on the Incidence of Postoperative Nausea and Vomiting
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|ClinicalTrials.gov Identifier: NCT03313479|
Recruitment Status : Not yet recruiting
First Posted : October 18, 2017
Last Update Posted : October 18, 2017
|Condition or disease||Intervention/treatment|
|Post Operative Nausea and Vomiting||Drug: Dexmedetomidine|
Postoperative nausea and vomiting (PONV) is a distressing adverse effect that may result in postoperative complications including bleeding, wound dehiscence, aspiration pneumonitis, as well as fluid and electrolyte imbalances.
The incidence of PONV after general anesthesia is about 30% in all post-surgical patients but up to 80% in high-risk patients despite advances in anesthetics and anesthesia techniques.
Despite new antiemetic drugs the overall incidences remain high especially in subjects with increased patient-related risk-factors such as in female gender, non-smoking status, a history of motion sickness or previous PONV, inhalational anesthetics, certain types of surgery, and opioid use. Scleral buckling (SB) which is still thought to be the most efficacious and cost-effective primary procedure for the treatment of uncomplicated retinal detachment is often associated with postoperative pain as well as nausea and vomiting. Preoperative injections of local anesthetics via retrobulbar, peribulbar, or subtenon routes in patients undergoing vitreoretinal surgery under general anesthesia (GA) have been reported to reduce postoperative pain, nausea, and vomiting.
Topical lidocaine drops have also has been used intraoperatively to decrease the incidence and severity of the OCR and to prevent pain and PONV after strabismus surgery and vitrectomy without scleral buckling .
The current study was designed to compare the effect of three different analgesic techniques ; IV analgesia , peribulbar block and topical xylocaine jel on the incidence of ponv after scleral buckling under general anesthesia.
|Study Type :||Observational|
|Estimated Enrollment :||75 participants|
|Official Title:||Comparative Study of the Effect of Three Different Analgesic Techniques on the Incidence of Postoperative Nausea and Vomiting After Scleral Buckling Under General Anesthesia|
|Anticipated Study Start Date :||October 30, 2017|
|Estimated Primary Completion Date :||November 30, 2017|
|Estimated Study Completion Date :||January 1, 2018|
GA and Dexmedetomidine
Dexmedetomidine will be given with GS
Other Name: Dexmedetomidine with scleral buckling
GA and peribulbar
GA and xylocaine gel
- PONV [ Time Frame: 8 hours post operative ]incidence of post operative nausea and vomiting
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT03313479
|Contact: Hassan Ali, firstname.lastname@example.org|
|Contact: Ahmed Badwy, email@example.com|
|Cairo, Giza, Egypt, 1234|
|Contact: HASSAN M ALI, LECTURER +201001733687 firstname.lastname@example.org|