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This study will investigate the interplay of different immune cells and placental cells as well as their potential for the development of pregnancy complications. In particular, the translation of the uteroplacental syndrome into a maternal syndrome, considered in the multifactorial pregnancy disorder preeclampsia, will be investigated. Immune cell subtypes are causally involved in the formation and translation of preeclampsia by inducing an endothelial dysfunction which leads to cardiovascular damage.
Condition or disease
PreeclampsiaPregnancy ComplicationsDiabetes Mellitus in Pregnancy
T cell population content at the time of preeclampsia diagnosis compared to controls and verified by flow cytometry [ Time Frame: at the time of preeclampsia diagnosis compared to controls at the same time point in pregnancy ]
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Layout table for eligibility information
Ages Eligible for Study:
18 Years to 45 Years (Adult)
Sexes Eligible for Study:
Accepts Healthy Volunteers:
Pregnant women between 18 and 45 years of age without infections, severe or chronic diseases
healthy pregnant women after giving informed consent
pregnant with diagnosis of preeclampsia, gestational hypertension or gestational diabetes