Aflatoxin Birth Cohort Study Nepal (AflaCohort) (AflaCohort)
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The study focuses on the causal relationship between mycotoxin exposure (particularly aflatoxin B1), birth outcomes, and height for age among young children in Nepal. Previous studies have shown a strong association of stunting with mycotoxin exposure yet causality has not been proven. Thus, this study will provide a better understanding of the association between maternal and/or early life mycotoxin exposure (rates in the blood and breast milk) and infant and young child growth. This information is essential if we are to more fully understand and effectively address the high rates of stunting in Asia.
Condition or disease
StuntingBirth WeightBirth LengthHeight for AgeLinear Growth Failure
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Ages Eligible for Study:
16 Years to 49 Years (Child, Adult)
Sexes Eligible for Study:
Gender Based Eligibility:
Gender Eligibility Description:
Pregnant women and adolescent girls
Accepts Healthy Volunteers:
All pregnant women and adolescent girls aged 16-49 years and living in the study areas will be invited to join the study. Women who are less than 30 weeks into their gestation will be eligible to participate if their expected delivery date falls within the enrollment period.
Pregnant women and adolescent girls (less than 30 weeks gestation)
Aged 16-49 years
Living in the study area
Intends to reside in the study area through the study period
Intends to deliver in the study area
Provides informed consent herself or through a legal guardian
Severely malnourished mother <17.5 cm
Severely anemic mother hemoglobin<7 g/dL
Pregnancy induced hypertension
Very low birth weight <1500 g
Respiratory distress syndrome
Severe malnutrition infant ≤-3 WFH z-score (3 months), <11.5 cm MUAC or edema