Predictability of the Effects of Facet Joint Infiltration in the Degenerate Lumbar Spine When Assessing MRI Scans
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ClinicalTrials.gov Identifier: NCT03308149
Recruitment Status :
First Posted : October 12, 2017
Last Update Posted : October 12, 2017
University Hospital Tuebingen
Information provided by (Responsible Party):
Dr. Ulf Krister Hofmann, University Hospital Tuebingen
Fifty MRI scans of patients with chronic lumbar back pain were graded radiologically using a wide range of classification and measurement systems. The reported effect of facet joint injections at the site was recorded and a comparative analysis performed.
Condition or disease
Infiltration Facet Joint
Drug: infiltration with triamcinolone and bupivacaine
Correlation of radiologic findings and reported pain relief [ Time Frame: Improvement in pain level within 24 hours ]
Pain relief is assessed as an improvement in % on the NRS. Radiologic findings consist of numerous classification systems and measurement techniques to evaluate and classify spinals and neural foramen stenosis, like for example as suggested by Schizas, or the sagittal diameter of the spinal canal
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Ages Eligible for Study:
Child, Adult, Older Adult
Sexes Eligible for Study:
Accepts Healthy Volunteers:
All patients who had received inpatient gradual diagnostics in our department
patients who had received inpatient gradual diagnostics for chronic lumbar back pain
monosegmental facet joint infiltration on the first day of inpatient gradual diagnostics
clearly stated pain relief in percentage (%) for that specific infiltration in the medical documentation
pain level prior to infiltration needed to be clearly documented
a high-quality MRI available before infiltration.
ositive history of lumbar surgery or the presence of artificial implants in the area of interest
Individual Participant Data (IPD) Sharing Statement:
Plan to Share IPD:
General data file from which statistical analyses were performed may be requested from the authors after publication
Studies a U.S. FDA-regulated Drug Product:
Studies a U.S. FDA-regulated Device Product:
Additional relevant MeSH terms:
Central Nervous System Depressants
Physiological Effects of Drugs
Sensory System Agents
Peripheral Nervous System Agents
Hormones, Hormone Substitutes, and Hormone Antagonists
Molecular Mechanisms of Pharmacological Action