WTC Chest CT Imaging Archive
|The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.|
|ClinicalTrials.gov Identifier: NCT03295279|
Recruitment Status : Active, not recruiting
First Posted : September 27, 2017
Last Update Posted : May 14, 2019
|Condition or disease|
|Chronic Airway Disease Interstitial Lung Disease Lung Cancer|
|Study Type :||Observational|
|Actual Enrollment :||1722 participants|
|Official Title:||Pulmonary Diseases in WTC Workers: Symptoms, Function, and Chest CT Correlates|
|Actual Study Start Date :||January 15, 2013|
|Estimated Primary Completion Date :||August 31, 2021|
|Estimated Study Completion Date :||August 31, 2021|
- Accelerated longitudinal FEV1 decline [ Time Frame: 5 years ]The clinical team selects spirometries of acceptable quality, and subjects with at least 3 spirometries spanning at least 5 years, to calculate FEV1 slope, which can then be modeled quantitatively. For categorical analyses, the clinical team defines rapid FEV1 decliners and contrast them to normal-and-stable FEV1 subjects, defined as those having an FEV1 above the lower limit of normal at baseline, no bronchodilator response, and FEV1 not changing by more than 25 ml/year on average in either direction.
- Number of physician diagnosis of incident asthma [ Time Frame: 5 years ]Physician diagnosis of asthma with onset after WTC occupational exposures.
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT03295279
|United States, New York|
|Icahn School of Medicine at Mount Sinai|
|New York, New York, United States, 10029|
|Principal Investigator:||Rafael E. de la Hoz, MD, MPH, MSc||Icahn School of Medicine at Mount Sinai|