Drug Induced Submental Ultrasound in Obstructive Sleep Apnea Patients
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|ClinicalTrials.gov Identifier: NCT03285451|
Recruitment Status : Unknown
Verified May 2017 by Taipei Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation.
Recruitment status was: Recruiting
First Posted : September 18, 2017
Last Update Posted : September 18, 2017
|Condition or disease||Intervention/treatment|
|Obstructive Sleep Apnea||Diagnostic Test: submental ultrasonography|
Obstructive sleep apnea (OSA) is a syndrome characterized by recurrent episodes of apnea and hypopnea during sleep that are caused by repetitive upper airway (UA) collapse and often result in decreased blood oxygen levels and arousal from sleep. Successful treatment lies in precise mapping the site of airway narrowing.
Drug-induced sleep endoscopy (DISE) is a well described modality to mimic the dynamic change of UA in OSA patients during natural sleep. Nevertheless, the tongue base thickness (TBT), one of the important anatomic factors in OSA, is hard to evaluate under this method. Recently, submental ultrasound (US), the noninvasive and convenient tool, has been widely applied to measure the TBT in awake OSA patients, so as to predict the severity and relationship with UA collapse. However, few evidence has addressed the relationship between UA collapse and the TBT in different head positions, awake and sleep period In this study, submental US during awake and drug induced sleep period is applied in the diagnostic workup of OSA patients. By correlation with DISE findings, more parameters could be used for evaluation and management of upper airway collapse in OSA patients.
Key Words: Submental ultrasound, Obstructive sleep apnea, Drug-induced sleep endoscopy
|Study Type :||Observational|
|Estimated Enrollment :||100 participants|
|Official Title:||Correlative Analysis of Upper Airway Collapse in Sleep Endoscope and Submental Ultrasound|
|Actual Study Start Date :||May 1, 2017|
|Estimated Primary Completion Date :||May 1, 2020|
|Estimated Study Completion Date :||May 1, 2020|
- Diagnostic Test: submental ultrasonography
Submental ultrasound, the noninvasive and convenient tool, has been widely applied to measure the tongue base thickness in patients with obstructive sleep apnea, so as to predict the severity and relationship with upper airway collapse.
- The value of drug induced sleep ultrasonography in patients with obstructive sleep apnea [ Time Frame: May, 2017 to Aug, 2017 ]In this study, we proposed a novel method, drug induced sleep ultrasonography (DISU), which was applied to measure the tongue base thickness in OSA patients during drug induced sleep, so as to further understand the impact of dynamic change of tongue base thickness in OSA patients.
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Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT03285451
|Contact: Ming-Chin Lan, MDfirstname.lastname@example.org|
|Taipei Tzu Chi Hospital Buddhist Tzu Chi Medical Foundation||Recruiting|
|Taipei, Taiwan, 231|
|Contact: Ming-Chin Lan, MD +886920734552 email@example.com|
|Study Chair:||Ming-Chin Lan, MD||Taipei Tzu Chi Hospita l Buddhist Tzu Chi Medical Foundation|