Effects of Repeated Memory Training on Memory Function and Addiction Related Processes
|The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Know the risks and potential benefits of clinical studies and talk to your health care provider before participating. Read our disclaimer for details.|
|ClinicalTrials.gov Identifier: NCT03285256|
Recruitment Status : Recruiting
First Posted : September 15, 2017
Last Update Posted : May 7, 2018
|Condition or disease||Intervention/treatment||Phase|
|Substance-Related Disorders||Behavioral: Experimental memory training Behavioral: Comparator memory training 1 Behavioral: Comparator memory training 2||Not Applicable|
|Study Type :||Interventional (Clinical Trial)|
|Estimated Enrollment :||105 participants|
|Intervention Model:||Parallel Assignment|
|Intervention Model Description:||Participants will be randomly assigned to one of three treatment conditions: an experimental memory training program or one of two comparator memory training programs.|
|Masking:||Double (Participant, Investigator)|
|Masking Description:||Both the participant and the research assistant conducting the assessments will be blinded to group assignment.|
|Official Title:||Effects of Repeated Memory Training on Memory Function and Addiction Related Processes|
|Actual Study Start Date :||May 1, 2018|
|Estimated Primary Completion Date :||October 2020|
|Estimated Study Completion Date :||November 2020|
Experimental: Experimental Memory Training
Experimental memory training program
Behavioral: Experimental memory training
The experimental memory training will be implemented as a computer program that uses state-of-the-art immersive technology to simulate prospective memory in everyday life in which one must remember to carry out tasks throughout the day, while engaging in current ongoing activity. Participants are asked to imagine they have a work-at-home job (ongoing activity), which is an independent program (CogMed QM) designed to train working memory, but that they also need to remember to carry out a number of tasks throughout the day. Using a touch screen, participants will need to touch objects in the simulated environment to appropriately interact with these stimuli according to their pre-assigned tasks.
Active Comparator: Comparator Memory Training 1
Comparator memory training program
Behavioral: Comparator memory training 1
The first comparator memory training intervention will utilize the same overall structure and immersive computer environment as the experimental memory intervention, but will not challenge the same aspects of cognition.
Active Comparator: Comparator Memory Training 2
Alternative comparator memory training program
Behavioral: Comparator memory training 2
The second comparator memory training intervention will utilize the same overall structure and immersive computer environment as the experimental memory intervention, but will not challenge the same aspects of cognition.
- Change in prospective memory over course of training [ Time Frame: one month ]Prospective memory will be evaluated within the program itself and measured as the percentage of correct responses within the program. Higher percentages are indicative of greater prospective memory performance.
- Change in drug use and substance abuse over course of training. [ Time Frame: one month ]Drug use will be evaluated by urinalysis. Negative screens are indicative of drug abstinence.
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT03285256
|Contact: Research Program Coordinatorfirstname.lastname@example.org|
|United States, Maryland|
|Johns Hopkins University School of Medicine, Bayview Campus||Recruiting|
|Baltimore, Maryland, United States, 21224|
|Contact: Research Program Coordinator 410-550-5250 email@example.com|
|Principal Investigator: Matthew W Johnson, Ph.D.|
|Principal Investigator:||Matthew W Johnson, Ph.D.||Johns Hopkins University|