Psychiatric Comorbidities in Patients With Painful Peripheral Neuropathy
|The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Know the risks and potential benefits of clinical studies and talk to your health care provider before participating. Read our disclaimer for details.|
|ClinicalTrials.gov Identifier: NCT03275233|
Recruitment Status : Not yet recruiting
First Posted : September 7, 2017
Last Update Posted : July 10, 2018
|Condition or disease|
|Painful Peripheral Neuropathy|
Neuropathic pain has been redefined by the International Association for the Study of Pain, as'' pain caused by a lesion or disease of somatosensory system''.Diabetic peripheral neuropathy is the result of nerve damage in the toes, feet, and hands . Approximately 50% of those diabetic peripheral neuropathy have neuropathic pain .
Patients with persistent neuropathic pain experience work disability and activity limitation, with a substantial impact on their social functioning. As any chronic pain state comorbid depression, anxiety and sleep disturbance are common occurring in up to one half of those with painful neuropathy.
The relationship between chronic pain and cognitive function has not been adequately studied and little is known about cognitive functioning in neuropathic conditions. This may be because the clinicians pay more attention to psychiatric comorbidities, such as depression and anxiety.Although chronic pain associated with cognitive deficits may impact on everyday behaviour and interfere with emotional decision-making tasks.
In a cross-sectional survey at the Mayo clinic, the prevalence of clinician-diagnosed symptomatic or painful diabetic peripheral neuropathy was 13-15% out of 78% of those with any type of diabetic peripheral neuropathy . Many patients with diabetic peripheral neuropathy experience neuropathic pain, typically characterized as burning, electric, sharp and shooting which initially starts in both feet and may progress to involve calves, fingers, and hands (stocking and glove pattern) .
Recently it has been demonstrated an association between diabetes , diabetes complication and impairment of mental health and particular emphasis has been placed on the association between painful diabetic sensory neuropathy with depression .
|Study Type :||Observational|
|Estimated Enrollment :||40 participants|
|Official Title:||Psychiatric Comorbidities in Patient With Painful Peripheral Neuropathy|
|Estimated Study Start Date :||January 4, 2019|
|Estimated Primary Completion Date :||January 4, 2020|
|Estimated Study Completion Date :||January 4, 2021|
- Psychiatric comorbidities in diabetic patients with painful(symptomatic)peripheral neuropathy. [ Time Frame: 6 month ]1- Pain assessment using visual analogue scale (VAS).
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT03275233
|Contact: Noha Mohamed Abo Elfetoh, Professoremail@example.com|