Brain Network Activation Analysis in Epilepsy
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|ClinicalTrials.gov Identifier: NCT03265925|
Recruitment Status : Completed
First Posted : August 29, 2017
Last Update Posted : September 27, 2018
|Condition or disease|
|Epilepsy Epilepsy, Temporal Lobe|
BNA technology is based on a network model to depict functional connectivity. The descriptive network model approach provides insights regarding inter-connectivity of brain networks and can describe the temporal-spatial brain activation patterns applied to various types of data-sets including EEG, MEG and fMRI.
In this study it is proposed that synchronization in brain activity may be disrupted in patients who experience frequent seizures and may correspond to functional impairments (e.g., memory, processing speed). As such, BNA analysis may provide additional data that complement current functional assessments, inform clinical assessment and management of epilepsy, and identify subgroups of patients that might be at risk for poor treatment outcomes.
|Study Type :||Observational|
|Actual Enrollment :||1 participants|
|Official Title:||Brain Network Activation Analysis in Epilepsy|
|Actual Study Start Date :||May 26, 2017|
|Actual Primary Completion Date :||May 8, 2018|
|Actual Study Completion Date :||May 8, 2018|
Epilepsy patients Right Temporal Lobe
Epilepsy patients with seizures originating from the right temporal lobe
Epilepsy patients Left Temporal Lobe
Epilepsy patients with seizures originating from the left temporal lobe
- Assess the BNA database for Epilepsy population and healthy controls. [ Time Frame: Epilepsy subjects will perform the BNA testing at baseline prior to change in medication if applicable and 3-10 days following change in medication when applicable. ]Functional networks of brain activity in Epilepsy (Right and Left lobe) and healthy control individuals measured using analysis of EEG Event Related Potential (ERP) data. Clinical assessments battery will be utilized in order to examine different sets of BNA database for Epilepsy pathology and healthy controls.
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT03265925
|United States, Illinois|
|RUSH University medical center|
|Chicago, Illinois, United States, 60612|
|Principal Investigator:||Travis Stoub, PhD|