TRACE E-learning Implementation in Belgium
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|ClinicalTrials.gov Identifier: NCT03265028|
Recruitment Status : Completed
First Posted : August 29, 2017
Last Update Posted : August 30, 2019
Antibiotic resistance is a worldwide health care problem. Increasing use of antibiotics is associated with an increase in the prevalence of bacteria resistant to the antibiotic used. Reducing antibiotic use can be effected by improving antibiotic prescribing quality in two complementary ways. One is to limit antibiotic prescribing to those patients who will benefit from the treatment and two is to prescribe these patients the recommended antibiotic.
International research has shown that a web-based communication training for the prescriber combined with an interactive booklet containing relevant patient information (Genomics to combat Resistance against Antibiotics for Community acquired LRTI in Europe INternet Training for Reducing antibiOtic use (GRACE INTRO)) can significantly and safely reduce antibiotic prescribing in adults presenting to primary care with acute cough/lower respiratory tract infections (LRTI). Quality assessment of antibiotic prescribing for respiratory infections in general practice has revealed the use of far too many (broad-spectrum) antibiotics in Belgium.
In the proposed project, the investigators aspire to make Belgium the first European country to implement the most cost-effective part of the GRACE INTRO intervention (Translational Research on Antimicrobial resistance and Community-acquired infections in Europe (TRACE) e-learning, www.acutecough.org) at national level and to perform a scientifically sound assessment of the nationwide implementation on outpatient antibiotic use and societal cost.
|Condition or disease||Intervention/treatment|
|Respiratory Tract Infections||Behavioral: TRACE e-learning|
|Study Type :||Observational [Patient Registry]|
|Actual Enrollment :||15802 participants|
|Observational Model:||Ecologic or Community|
|Target Follow-Up Duration:||2 Years|
|Official Title:||National Implementation of a Multifaceted Web-based Communication Training to Reduce of Inappropriate Antibiotic Prescribing for (Lower) Respiratory Tract Infections|
|Actual Study Start Date :||September 1, 2017|
|Actual Primary Completion Date :||December 31, 2018|
|Actual Study Completion Date :||December 31, 2018|
Invited to take the TRACE e-learning.
Behavioral: TRACE e-learning
The TRACE e-learning (www.acutecough.org) is an educational web-based module including communication training for physicians, and includes patient booklets to be used interactively during the consultation.
Not (yet) invited to take the TRACE e-learning.
- Antibiotic use (short term) [ Time Frame: First 2 months after intervention ]Number of packages for antibacterials for systemic use (ATC J01) collected at the pharmacy (reimbursement data) per 1000 inhabitants per day
- Antibiotic use (intermediate term) [ Time Frame: 3-6 months after intervention ]Number of packages for antibacterials for systemic use (ATC J01) collected at the pharmacy (reimbursement data) per 1000 inhabitants per day
- Antibiotic use (long term) [ Time Frame: 6-12 months after intervention ]Number of packages for antibacterials for systemic use (ATC J01) collected at the pharmacy (reimbursement data) per 1000 inhabitants per day
- Response rate (short term) [ Time Frame: First 2 months after intervention ]The number of invited GPs taking the TRACE e-learning
- Response rate (long term) [ Time Frame: First year after intervention ]The number of invited GPs taking the TRACE e-learning
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT03265028
|GPs of Henegouwen|
|Mons, Henegouwen, Belgium|
|GPs of Limburg|
|Hasselt, Limburg, Belgium|
|GPS of Luik|
|Liège, Luik, Belgium|
|Gps of Luxemburg|
|Arlon, Luxemburg, Belgium|
|GPs of Namen|
|Namur, Namen, Belgium|
|GPs of Oost-Vlaanderen|
|Gent, Oost-Vlaanderen, Belgium|
|GPs of Vlaams-Brabant|
|Leuven, Vlaams-Brabant, Belgium|
|GPs of Waals-Brabant|
|Wavre, Waals-Brabant, Belgium|
|GPs of West-Vlaanderen|
|Brugge, West-Vlaanderen, Belgium|
|GPs of Antwerp|
|GPs of Brussels|
|Principal Investigator:||Samuel Coenen, Prof||Universiteit Antwerpen|