Detection of Asymptomatic Venous Thrombosis in Gynecological Patients With Pelvic Masses
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|ClinicalTrials.gov Identifier: NCT03260270|
Recruitment Status : Not yet recruiting
First Posted : August 24, 2017
Last Update Posted : August 24, 2017
|Condition or disease||Intervention/treatment|
|Silent; Thrombosis||Diagnostic Test: color doppler ultrasound|
High incidence of silent VTE before surgery seems attributable to the high incidence of VTE after surgery in ovarian cancer .
The incidence rate of DVT is about 10% to 40% in medical or general surgical patients without prophylaxis .With prophylaxis, the postoperative incidence of VTE was 1.14% in women with gynecological disease, and 0.7% in patients undergoing laparoscopic gynecological surgery, 0.3% in patients undergoing urogynecological surgery, and 4% in gynecological cancer patients, respectively. Most of published studies enrolled only symptomatic patients with DVT, whereas asymptomatic patients could be easily neglected under the absence of effective detection. In fact, approximately 50% of DVT patients are silent, so the actual incidence of postoperative DVT might be higher than reported . The asymptomatic DVT has been confirmed to increase the development of post-thrombotic syndrome (PTS).
The essence of any surveillance strategy would be the identification of DVT in the expectation that anticoagulation at the presymptomatic stage would prevent fatal pulmonary embolism .
A number of imaging modalities are currently available to evaluate deep venous system in a comprehensive manner allowing correct assessment of presence of thrombosis . Color Doppler ultrasound has become the primary non invasive diagnostic method for DVT.
All patients are going to be examined by color Doppler ultrasound and by direct MDCT venography .
|Study Type :||Observational [Patient Registry]|
|Estimated Enrollment :||60 participants|
|Target Follow-Up Duration:||1 Week|
|Official Title:||Detection of Asymptomatic Venous Thrombosis in Gynecological Patients With Pelvic Masses|
|Estimated Study Start Date :||September 2017|
|Estimated Primary Completion Date :||September 2020|
|Estimated Study Completion Date :||December 2020|
- Diagnostic Test: color doppler ultrasound
All patients are going to be examined by color Doppler ultrasound and the high risk patients are going to be examined by direct MDCT venography .Other Name: direct MDCT venography
- detection of asymptomatic venous thrombosis [ Time Frame: one week before operation ]silent venous thrombosis in gynecological patients with pelvic masses
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT03260270
|Contact: Dr. Gehan Sayed, assit firstname.lastname@example.org|
|Contact: Dr.Omran Khodary, lecturer||00201117298484|