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Trial record 12 of 7516 for:    Type 2 Diabetes

Fish, Polyunsaturated Fatty Acids Intake and Type 2 Diabetes

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ClinicalTrials.gov Identifier: NCT03259321
Recruitment Status : Completed
First Posted : August 23, 2017
Last Update Posted : August 23, 2017
Sponsor:
Collaborator:
Information provided by (Responsible Party):

Study Description
Brief Summary:
The role of fishery diet and polyunsaturated fatty acids (PUFA) in the development of type 2 diabetes (T2D) is heavily debated but evidence from large populations in China is scant. We aim to use data from the China Health and Nutrition Survey (CHNS) to assess the long-term association between fish, PUFA intake and T2D risk.

Condition or disease
Type2 Diabetes

Detailed Description:
The role of fishery diet and polyunsaturated fatty acids (PUFA) in the development of T2D is heavily debated but evidence from large populations in China is still lacking. We aim to utilize data from China Health and Nutrition Survey (CHNS, 1997-2011). We will calculate cumulative means of fish and PUFA intake based on 3-day food records in each wave. Sex-specific Cox regression models will be used to estimate relative risk of T2D. Results from this work will provide epidemiological evidence for improving recommendations on fish and PUFA intake for Chinese in dietary guidelines.

Study Design

Study Type : Observational
Actual Enrollment : 15100 participants
Observational Model: Cohort
Time Perspective: Prospective
Official Title: Fish, Polyunsaturated Fatty Acids Intake and Type 2 Diabetes in CHNS
Actual Study Start Date : January 1, 1989
Primary Completion Date : December 31, 2011
Study Completion Date : December 31, 2012

Resource links provided by the National Library of Medicine

U.S. FDA Resources

Groups and Cohorts


Outcome Measures

Primary Outcome Measures :
  1. Type 2 diabetes [ Time Frame: From entry into the study (baseline: 1997-2009) until 2011 ]
    Incidence of type 2 diabetes, on basis of self-reported physician diagnosis, fasting plasma glucose ≥ 7.0 mmol/l or HbA1c ≥ 6.5%


Secondary Outcome Measures :
  1. Fish and polyunsaturated fatty acids intake [ Time Frame: From entry into the study (baseline: 1997-2009) until 2011 ]
    Cumulative averages of fish and PUFA intake based on 3-day 24-hr recall in each wave


Eligibility Criteria

Information from the National Library of Medicine

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Ages Eligible for Study:   20 Years and older   (Adult, Senior)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes
Sampling Method:   Probability Sample
Study Population
CHNS is an ongoing, large-scale, household-based cohort starting in 1989. The survey used a multi-stage, random cluster process to draw a sample of 9 provinces and municipal cities, which take up about half of Chinese population.
Criteria

Inclusion Criteria:

  • Adults aged ≥20 with complete data on diet and follow-up time

Exclusion Criteria:

  • Missing information for Type 2 diabetes
  • Type 2 diabetes
  • Cardiovascular disease
More Information

Responsible Party: Jingjing Jiao, Associate Professor, Zhejiang University
ClinicalTrials.gov Identifier: NCT03259321     History of Changes
Other Study ID Numbers: Cohort_PUFA_T2D
First Posted: August 23, 2017    Key Record Dates
Last Update Posted: August 23, 2017
Last Verified: July 2017

Studies a U.S. FDA-regulated Drug Product: No
Studies a U.S. FDA-regulated Device Product: No

Keywords provided by Jingjing Jiao, Zhejiang University:
Fish
Polyunsaturated fatty acids
CHNS

Additional relevant MeSH terms:
Diabetes Mellitus
Diabetes Mellitus, Type 2
Glucose Metabolism Disorders
Metabolic Diseases
Endocrine System Diseases