Detection of Hepatitis C Infection by Oraquick Test Among Health Care Workers
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|ClinicalTrials.gov Identifier: NCT03254901|
Recruitment Status : Not yet recruiting
First Posted : August 21, 2017
Last Update Posted : August 21, 2017
|Condition or disease||Intervention/treatment|
|Hepatitis C||Other: Screening test by Oraquick test|
Hepatitis C is a chronic disease affecting approximately 130-170 million people worldwide. According to the world health organization, annually, more than 399,000 people die from hepatitis C-related liver diseases and 3-4 million people are infected with hepatitis C virus . Approximately 3% of the world's population is estimated to be infected with hepatitis C virus .
Hepatitis C is found worldwide. World health organization documented that Eastern Mediterranean and European regions are the most affected regions, with the prevalence of 2.3% and 1.5% respectively. Prevalence of hepatitis C virus infection in other world health organization regions varies from 0.5% to 1.0%. There are multiple strains ( genotypes) of the hepatitis C virus and their distribution varies by region.
Available data indicate that infection with hepatitis C virus infection varies considerably by country and region and countries believed to have the highest rate of chronic hepatitis C virus infection are Egypt (15 %), Pakistan (4.8 %), and China (3.2 %). However, the true incidence of the disease is not well known in many countries, because acute infection is generally asymptomatic.
The Egyptian Demographic Health Survey ( 2008), which was conducted on a large nationally representative sample, estimated the prevalence of hepatitis C virus antibodies and hepatitis C virus nucleic acid, among the 15-59 years age group, to be 14.7 and 9.8% respectively. On the other hand, the prevalence of hepatitis C virus antibodies and hepatitis C virus nucleic acid, among the 15-59 years age group, to be 10 and 7 % respectively according to the Egyptian Health Issues Survey ( 2015).There was an overall significant reduction of 32 %and 29% in the prevalence of Hepatitis C virus antibody and Hepatitis C virus nucleic acid-positive individuals, respectively, between the Egyptian Demographic Health Survey in 2008 and the the Egyptian Health Issues Survey in 2015.
Hepatitis C virus is a bloodborne virus. It is most commonly transmitted through injecting drug use through the sharing of injection equipment; the reuse or inadequate sterilization of medical equipment, especially syringes and needles in healthcare settings; and the transfusion of unscreened blood and blood products.
hepatitis C virus can also be transmitted sexually and can be passed from an infected mother to her baby; however these modes of transmission are much less common, while it is not spread through breast milk, food, water or by casual contact such as hugging, kissing and sharing food or drinks with an infected person.
|Study Type :||Observational|
|Estimated Enrollment :||1200 participants|
|Official Title:||Detection of Hepatitis C Infection by Oraquick Test Among Health Care Workers in Assiut Governorate and Treatment Outcome Among True Positive Cases|
|Estimated Study Start Date :||January 1, 2018|
|Estimated Primary Completion Date :||June 1, 2018|
|Estimated Study Completion Date :||July 1, 2018|
health care workers
health care workers in Assiut health directorate, Abutig central hospital, El-Quseya central hospital and Sahil selim central hospital in Assiut governorate .All of them will be screened for hepatitis C infection and interviewed about mode of transmission of infection
Other: Screening test by Oraquick test
The OraQuick assay uses an indirect immunoassay method to detect hepatitis C antibodies in oral fluid or blood
- percentage of hepatitis C virus infection among health care workers [ Time Frame: six months ]hepatitis C infection is screened by oraquick test the confirmed by hepatitis C nucleic acid testing
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT03254901
|Contact: Mohammad Qayed, MDfirstname.lastname@example.org|
|Contact: Ekram Mohamed, MDemail@example.com|
|Assiut university||Not yet recruiting|
|Assiut, Egypt, 71111|
|Contact: Asmaa Soliman, MD 01006445030 firstname.lastname@example.org|