Effect of Endometrial Injury Before Frozen Embryo Transfer on Pregnancy Rate
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|ClinicalTrials.gov Identifier: NCT03220503|
Recruitment Status : Unknown
Verified July 2017 by Yasser sherbiny, Ain Shams Maternity Hospital.
Recruitment status was: Recruiting
First Posted : July 18, 2017
Last Update Posted : July 18, 2017
In women undergoing frozen embryo transfer, does routine endometrial injury before frozen embryo transfer increase clinical pregnancy rate?
(Null Hypothesis) In women undergoing frozen embryo transfer Routine endometrial injury before frozen embryo transfer does not increase clinical pregnancy rate.
(Alternative Hypothesis) In women undergoing frozen embryo transfer, endometrial injury before the transfer may increase pregnancy rate.
|Condition or disease||Intervention/treatment||Phase|
|Infertility||Procedure: endometrial injury||Phase 4|
|Study Type :||Interventional (Clinical Trial)|
|Estimated Enrollment :||50 participants|
|Intervention Model:||Parallel Assignment|
|Masking:||None (Open Label)|
|Official Title:||Effect of Endometrial Injury Before Frozen Embryo Transfer on Pregnancy Rate|
|Actual Study Start Date :||March 8, 2017|
|Estimated Primary Completion Date :||September 9, 2017|
|Estimated Study Completion Date :||October 1, 2017|
Experimental: Group (A)
consists of 25 patients will receive frozen embryo with endometrial scratching on day 7 of transfer cycle.
Procedure: endometrial injury
single induced injury will be done on the posterior endometrium on day 7 of the transfer cycle by using modified Cook catheter.
No Intervention: Group (B)
consists of 25 patients will receive frozen embryo without endometrial scratching as control group.
- Chemical pregnancy rate [ Time Frame: two weeks after frozen embryo transfer ]serum Beta -Human Chorionic Gonadotropin positive
- Clinical pregnancy rate [ Time Frame: four weeks after frozen embryo transfer ]appearance of gestational sac on trans-vaginal ultrasound
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT03220503
|Contact: Yasser Sherbiny, firstname.lastname@example.org|
|ART unit - Ain Shams university Matrnity Hospital||Recruiting|
|Contact: yasser sherbiny, invistgator +201008961189 email@example.com|
|Study Director:||Adel Sh Salah El-Din, Ass. Prof.||Ain Shams University|
|Study Director:||Mohammed A Faris, Lecturer||Ain Shams University|
|Study Director:||Mohamed E Shawky, Lecturer||Ain Shams University|