Perceptual-Cognitive Training After a Mild Traumatic Brain Injury: Towards a Sensitive Marker for Recovery
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|ClinicalTrials.gov Identifier: NCT03213730|
Recruitment Status : Recruiting
First Posted : July 11, 2017
Last Update Posted : July 11, 2017
|Condition or disease||Intervention/treatment||Phase|
|Brain Concussion Post-Concussion Symptoms Concussion||Other: 3D-MOT Neurotracker Other: Visual Attention Intervention||Not Applicable|
|Study Type :||Interventional (Clinical Trial)|
|Estimated Enrollment :||90 participants|
|Intervention Model:||Parallel Assignment|
|Masking:||Single (Outcomes Assessor)|
|Official Title:||Perceptual-Cognitive Training After a Mild Traumatic Brain Injury: Towards a Sensitive Marker for Recovery|
|Actual Study Start Date :||January 10, 2017|
|Estimated Primary Completion Date :||April 30, 2019|
|Estimated Study Completion Date :||July 30, 2019|
Experimental: Experimental group
Standard care + 3D-MOT protocol.
Other: 3D-MOT Neurotracker
A predetermined number of spheres (eight) are presented in the 3D-MOT task. The spheres are all identical in shape and color. Before each trial, four spheres are highlighted, and then returned to their original color. Participants will be asked to track those four spheres for the duration of the trial (8 seconds). Spheres will be moving, bouncing, colliding, until they finally stop moving and the participant has to identify the spheres that were initially highlighted. Previous work with healthy individuals has shown that the minimum optimal number of sessions (3 blocks) necessary to induce brain plasticity and enhance other, "non-trained" brain functions is between 5-6. The training protocol will therefore include 6 sessions (3 blocks each), at intervals of 48 to 72 hours, over a maximum of 3 weeks.
Active Comparator: Active control group
Standard care + visual attention task (2048 online game)
Other: Visual Attention Intervention
The visual attention intervention will consist of the 2048 game, a single-player sliding block puzzle game of which the objective is to slide numbered tiles on a grid to combine them to create number 2048. 2048 is played on a gray 4×4 grid, with numbered tiles that slide smoothly when a player moves them using the four arrow keys. Every turn, a new tile will randomly appear in an empty spot on the board with a value of either 2 or 4.Tiles slide as far as possible in the chosen direction until they are stopped by either another tile or the edge of the grid. If two tiles of the same number collide while moving, they will merge into a tile with the total value of the two tiles that collided. Higher-scoring tiles emit a soft glow. Children will play for a time equivalent to that of the 3D-MOT.
No Intervention: Control group
Standard care alone
- Post Concussion Symptom Inventory [ Time Frame: 1 month ]Post-concussion symptoms checklist
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT03213730
|Contact: Isabelle Gagnon, PhD||514-412-4400 ext 23896|
|Montreal Children's Hospital, MUHC||Recruiting|
|Montreal, Quebec, Canada, H4A3J1|
|Contact: Isabelle Gagnon, PhD 514-412-4400 ext 23896 firstname.lastname@example.org|