Expanded Access to Provide LOXO-195 for the Treatment of Cancers With a NTRK Gene Fusion
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LOXO-195 expanded access is for patients with cancer with a NTRK1, NTRK2, or NTRK3 gene fusion who are ineligible for an ongoing LOXO-195 clinical trial or have other considerations that prevent access to LOXO-195 through an existing clinical trial. Expanded access is intended to treat individual patients with different types of cancers, including blood cancers, with a NTRK gene fusion who have previously received TRK inhibitor therapy
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Ages Eligible for Study:
Child, Adult, Older Adult
Sexes Eligible for Study:
Diagnosis of cancer with a NTRK1, NTRK2, and NTRK3 gene fusion
Previous treatment with a kinase inhibitor with known activity on TRK inhibition
Unable to participate in an ongoing LOXO-195 clinical trial
Willing and able to provide written, signed informed consent
Medically suitable for treatment with LOXO-195
- Currently enrolled in an ongoing clinical study with a TRK inhibitor