ZIKAlliance Natural History Study (ZIKAllianceNH)
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|ClinicalTrials.gov Identifier: NCT03204409|
Recruitment Status : Not yet recruiting
First Posted : July 2, 2017
Last Update Posted : July 2, 2017
|Condition or disease|
|Zika Virus Zika Virus Infection|
- Study to enroll up to 1000 adult patients (>18 years) presenting with febrile or rash illness of short duration (<72h) in designated clinics in the State of Sao Paulo, Brazil.
- Following enrolment (day 0), patients will be followed up at days 2-3, 7, 14, 21, 30, 90, 180 and 360 with clinical and biological procedures (blood and urine samples).
- For patients with proven ZIKA Virus (ZIKV) infection, follow-up samples will include blood, saliva, urine and genital samples.
- For non-ZIKV infected patients, follow-up samples will include serological monitoring at days 14, 30, 180 and 360, and for men, possible assessment of genital fluids at day 180.
- All patients will be evaluated for impact on disability up to one year. Household adult contacts of ZIKV patients will be invited for ZIKV evaluation including collection of blood and urine samples.
|Study Type :||Observational|
|Estimated Enrollment :||1000 participants|
|Official Title:||Longitudinal Clinical and Virological Study Among Symptomatic Patients With Zika Virus Infection in the City of Sao Paulo, Brazil|
|Estimated Study Start Date :||July 1, 2017|
|Estimated Primary Completion Date :||December 31, 2018|
|Estimated Study Completion Date :||September 3, 2019|
adult patients (>18 years) presenting with febrile or rash illness of short duration (<72h)
- ZIKA Virus Infection [ Time Frame: up to one year ]Clinical Characterization
- DENGUE Virus Infection [ Time Frame: up to one year ]Clinical Characterization
- Chikungunya Virus Infection [ Time Frame: up to one year ]Clinical Characterization
Biospecimen Retention: Samples With DNA
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT03204409
|Contact: Thomas Jänisch||+49 6221 56 email@example.com|
|University of Sao Paulo||Not yet recruiting|
|São Paulo, Brazil|
|Contact: Vivian Avelino-Silva firstname.lastname@example.org|
|Contact: Aluisio Cotrim Segurado email@example.com|
|Principal Investigator:||Thomas Jänisch||University Hospital Heidelberg|