Immersive Virtual Reality for Neuropathic Pain
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ClinicalTrials.gov Identifier: NCT03203772 |
Recruitment Status
:
Recruiting
First Posted
: June 29, 2017
Last Update Posted
: July 14, 2017
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Condition or disease | Intervention/treatment | Phase |
---|---|---|
Neuropathy Phantom Limb Pain Complex Regional Pain Syndromes Neuropathic Pain | Other: Immersive Virtual Reality | Not Applicable |
Study Type : | Interventional (Clinical Trial) |
Estimated Enrollment : | 20 participants |
Intervention Model: | Single Group Assignment |
Masking: | None (Open Label) |
Primary Purpose: | Treatment |
Official Title: | Management of Pain in Limb Neuropathic Conditions Through Immersive Virtual Reality |
Actual Study Start Date : | January 2016 |
Estimated Primary Completion Date : | January 2019 |
Estimated Study Completion Date : | January 2020 |

Arm | Intervention/treatment |
---|---|
Experimental: Limb neuropathic conditions
Includes phantom limb pain, complex regional pain syndrome
|
Other: Immersive Virtual Reality
Participants will engage in virtual visualization therapy in an immersive virtual reality environment
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- Feasibility of Virtual Reality Environment Use Questionnaire [ Time Frame: Immediately following final virtual reality session ]Using a questionnaire, feedback over participant self-reported tolerance of the virtual reality environment, participant likelihood of recommending this therapy to others with similar conditions, reported sense of presence in presented scenario(s), comfort of virtual reality devices, impact on self-reported functional ability outside of clinic, and overall impression of virtual reality therapy will be recorded.
- Pain Relief with Virtual Reality Therapy: Wong-Baker Scale [ Time Frame: Change from initial scores prior to virtual reality exposure to immediately prior to and following virtual reality sessions, and up to 8 weeks following last sessions ]Change in Wong-Baker Faces pain scale will be measured. This will be done by obtaining pain scale scores immediately prior to therapy session, immediately following therapy, and several weeks post last therapy session.
- Pain Relief with Virtual Reality Therapy: Visual Analog Scale [ Time Frame: Change from initial scores prior to virtual reality exposure to immediately prior to and following virtual reality sessions, and up to 8 weeks following last sessions ]Change in Visual Analog Pain Scale will be measured. This will be done by obtaining pain scale scores immediately prior to therapy session, immediately following therapy, and several weeks post last therapy session.
- Pain Relief with Virtual Reality Therapy: Short-Form McGill Pain Scale [ Time Frame: Change from initial scores prior to virtual reality exposure to immediately prior to and following virtual reality sessions, and up to 8 weeks following last sessions ]Change in Short-Form McGill Pain Questionnaire will be measured. This will be done by obtaining pain scale scores immediately prior to therapy session, immediately following therapy, and several weeks post last therapy session.

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Ages Eligible for Study: | 12 Years and older (Child, Adult, Senior) |
Sexes Eligible for Study: | All |
Accepts Healthy Volunteers: | No |
Inclusion Criteria:
- Diagnosis of complex regional pain syndrome or phantom limb pain in an upper or lower limb
Exclusion Criteria:
- Cognitive impairment leading to inability to make own medical decisions
- Complete inability to utilize leg or arm muscles that are needed for motion controller tracking
- History of seizures within the last year

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT03203772
Contact: Brian Chau, MD | 909-558-6202 |
United States, California | |
Loma Linda University Health, East Campus Outpatient Rehabilitation Center | Recruiting |
Loma Linda, California, United States, 92354 | |
Contact: Brian Chau, MD 909-558-6202 bchau@llu.edu |
Principal Investigator: | Brian Chau, MD | Loma Linda Univeristy |
Responsible Party: | Brian Chau, Physician Instructor, Principle Investigator, Department of Physical Medicine and Rehabilitation, Loma Linda University |
ClinicalTrials.gov Identifier: | NCT03203772 History of Changes |
Other Study ID Numbers: |
5150437 |
First Posted: | June 29, 2017 Key Record Dates |
Last Update Posted: | July 14, 2017 |
Last Verified: | July 2017 |
Studies a U.S. FDA-regulated Drug Product: | No | |
Studies a U.S. FDA-regulated Device Product: | No |
Additional relevant MeSH terms:
Phantom Limb Neuralgia Complex Regional Pain Syndromes Reflex Sympathetic Dystrophy Pain Neurologic Manifestations Nervous System Diseases Peripheral Nervous System Diseases |
Neuromuscular Diseases Signs and Symptoms Perceptual Disorders Neurobehavioral Manifestations Pain, Postoperative Postoperative Complications Pathologic Processes Autonomic Nervous System Diseases |