Hypothyroidism in Patients With Type 2 Diabetes With Early Diabetic Nephropathy
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|ClinicalTrials.gov Identifier: NCT03178253|
Recruitment Status : Unknown
Verified June 2017 by maria hamdy, Assiut University.
Recruitment status was: Enrolling by invitation
First Posted : June 6, 2017
Last Update Posted : June 7, 2017
Diabetes Mellitus is the most common disorder seen. The impact of this disease on the quality of life, and on morbidity and mortality through the complications that affect the small and large vessels resulting in retinopathy, nephropathy, neuropathy, and ischemic heart disease has been emphasized by the findings of the national commission (USA) on diabetes .
So, there was curiosity to understand and learn the association of this disorder with another common endocrine gland function that is thyroid gland . The association between these two disorders has long been recognized although the prevalence of thyroid dysfunction in diabetic population varies widely between studies. With insulin and thyroid hormone being intimately involved in cellular metabolism and thus excess or deficit of these hormones result in functional derangement of the other.
|Condition or disease|
|Hypothyroidism in Diabetes|
Diabetic patients have higher prevalence of thyroid disorder when compared with the normal population. Diabetic women are more frequently affected than men and hypothyroidism is more common than thyrotoxicosis .
Sub-clinical hypothyroidism is an independent risk factor for development of diabetic nephropathy. Severe hypothyroidism (biochemically) may be completely asymptomatic. Though our patient had throid stimulating hormone level more than 100 mIU/L, he did not have any symptoms of hypothyroidism.so diagnosis of hypothyroidism depends on laboratory parameters rather than clinical findings Recognition and treatment of hypothyroidism in diabetic patients will benefit glycemic control and improve general well-being ). Diabetic nephropathy, a major micro-vascular complication of type 2 diabetes mellitus, is an important cause of chronic kidney disease. It results from interactions between hemodynamic and metabolic factors .
|Study Type :||Observational|
|Estimated Enrollment :||100 participants|
|Official Title:||Hypothyroidism in Patients With Type 2 Diabetes With Early Diabetic Nephropathy|
|Estimated Study Start Date :||June 30, 2017|
|Estimated Primary Completion Date :||June 30, 2017|
|Estimated Study Completion Date :||June 30, 2018|
- percentage of hypothyroidism in patients of type 2 diabetes with diabetic nephropathy [ Time Frame: one year ]
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Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT03178253