Epithelioid Hemangioma of Bone And Soft Tissue (EE-META)
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|ClinicalTrials.gov Identifier: NCT03169595|
Recruitment Status : Completed
First Posted : May 30, 2017
Last Update Posted : May 30, 2017
The controversy surrounding epithelioid hemangioma diagnosis stems from its somewhat aggressive clinical characteristics, including multifocal presentation and occasional lymph node involvement.
The investigators reviewed the clinicopathologic and radiologic characteristics of bone and soft tissue epithelioid hemangioma in patients treated at our institution with available tissue for molecular testing.
The hypothesis is that epithelioid hemangioma may present with multifocal involvement and rare loco-regional lymph node metastasis, but it remains a benign tumor with excellent prognosis.
|Condition or disease||Intervention/treatment|
|Epithelioid Hemangioma of Bone Epithelioid Hemangioma||Procedure: Surgery|
The investigators retrospectively reviewed patients treated for epithelioid hemangioma of the bone and soft tissue in a single insitution. The purpose of this study is to evaluate the pathological, clinical, and radiological characteristics of epithelioid hemangioma arising within bone and soft tissue, in the first cohort of cases where the definitive diagnosis is supplemented by molecular techniques.
The hypothesis is that the improved knowledge regarding this rare entity can more definitively elucidate the benign biology of epithelioid hemangioma.
|Study Type :||Observational|
|Actual Enrollment :||70 participants|
|Official Title:||Epithelioid Hemangioma of Bone And Soft Tissue: a Benign Tumor With Metastatic Potential|
|Actual Study Start Date :||October 7, 2015|
|Actual Primary Completion Date :||May 17, 2017|
|Actual Study Completion Date :||May 17, 2017|
- Procedure: Surgery
Patients affected by epithelioid hemangioma treated with surgery
- Multifocal presentation of patients with epithelioid hemangioma of bone and soft tissue without producing a fatal outcome [ Time Frame: 2 years ]The investigators defined multifocal presentation the presence of secondary lesions by imaging at presentation of the disease or during follow-up.
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT03169595
|Study Director:||Davide Donati, MD||Istituto Ortopedico Rizzoli|