Brain-to-Society Diagnostic for Prevention of Childhood Obesity and Chronic Disease
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|ClinicalTrials.gov Identifier: NCT03151694|
Recruitment Status : Unknown
Verified April 2017 by McGill University.
Recruitment status was: Active, not recruiting
First Posted : May 12, 2017
Last Update Posted : May 12, 2017
|Condition or disease|
|Study Type :||Observational|
|Actual Enrollment :||1224 participants|
|Official Title:||Foundational Work for a Brain-to-Society Diagnostic for Prevention of Childhood Obesity and Its Chronic Diseases Consequences|
|Actual Study Start Date :||February 1, 2011|
|Estimated Primary Completion Date :||January 31, 2019|
|Estimated Study Completion Date :||January 31, 2019|
DRD4 and DRD2 Polymorphism Detection
The genetic component of endophenotype for responsiveness to environment (ERE) will be characterized with reference to Taq1A allele in dopamine-2 receptor (DRD2) gene and the exon 3 7-repeat allele of the dopamine-4 receptor (DRD4) gene. This will assist in understanding the role of DRD2 and DRD4 in shaping the neurocognitive functions and link to the eating behaviors of the children and other primary outcome variables.
- Individual-level BtS Diagnostic 1 [ Time Frame: 2 years ]Genotyping and detection of the Taq1A allele in the dopamine-2 receptor (DRD2) gene.
- Individual-level BtS Diagnostic 2 [ Time Frame: 2 years ]Genotyping and detection of the exon 3 7-repeat allele of the dopamine-4 receptor (DRD4) gene.
- Behavioral Assessment [ Time Frame: 2 years ]Assess behavior of each participant in relation to food choice
- Body Weight Assessment [ Time Frame: 2 years ]Assess body weight of each participant
- Nutritional Risk Assessment [ Time Frame: 2 years ]Assess nutrition intake for each participant.
Biospecimen Retention: Samples With DNA
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT03151694
|McGill Centre for the Convergence of Health and Economics (MCCHE)|
|Montréal, Quebec, Canada, H3A 1X9|
|The INCLEN Trust International|
|New Delhi, India, 110020|
|Principal Investigator:||Laurette Dubé, Ph.D.||McGill University|