Effect of "Nicotinamide Mononucleotide" (NMN) on Cardiometabolic Function (NMN)
|The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.|
|ClinicalTrials.gov Identifier: NCT03151239|
Recruitment Status : Active, not recruiting
First Posted : May 12, 2017
Last Update Posted : June 23, 2020
|Condition or disease||Intervention/treatment||Phase|
|Glucose Metabolism Disorders||Dietary Supplement: NMN supplement Other: Placebo||Not Applicable|
|Study Type :||Interventional (Clinical Trial)|
|Actual Enrollment :||25 participants|
|Intervention Model:||Parallel Assignment|
|Masking:||Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)|
|Primary Purpose:||Basic Science|
|Official Title:||Effect of NMN (Nicotinomide Mononucleotide) Supplementation on Cardiometabolic Function|
|Actual Study Start Date :||July 1, 2017|
|Actual Primary Completion Date :||May 30, 2019|
|Estimated Study Completion Date :||May 30, 2021|
|Placebo Comparator: Placebo||
Intervention will last at least 8 weeks in the form of two capsules.
|Experimental: NMN supplementation||
Dietary Supplement: NMN supplement
Intervention will last at least 8 weeks in the form of two capsules (250 mg total).
Other Name: nicotinamide mononucleotide
- To determine change in insulin sensitivity. [ Time Frame: at least 8 weeks ]This will be determined by observing skeletal muscle insulin sensitivity (assessed by using the hyperinsulinemic-euglycemic clamp procedure in conjunction with stable isotope tracer infusion).
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT03151239
|United States, Missouri|
|Washington University School of Medicine|
|Saint Louis, Missouri, United States, 63110|
|Principal Investigator:||Samuel Klein, MD||Washington University School of Medicine|