Influence of Genetic Polymorphism of Donor on Tacrolimus Concentration in Liver Transplant
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|ClinicalTrials.gov Identifier: NCT03140462|
Recruitment Status : Unknown
Verified March 2017 by National Taiwan University Hospital.
Recruitment status was: Not yet recruiting
First Posted : May 4, 2017
Last Update Posted : May 4, 2017
|Condition or disease|
|Study Type :||Observational|
|Estimated Enrollment :||400 participants|
|Official Title:||The Influence of ABCB1、CYP3A4、CYP3A5、POR Genetic Polymorphism of Donor on Tacrolimus Blood Concentration in Liver Transplant Patients|
|Estimated Study Start Date :||May 2017|
|Estimated Primary Completion Date :||March 2018|
|Estimated Study Completion Date :||March 2019|
liver transplant patients and donors
To study clinical and genetic factors on tacrolimus dose normalized trough concentration.
- Dose normalized trough concentration of tacrolimus in liver transplant patients within the first 6 months post-transplantation [ Time Frame: Within the first 6 months post-transplantation ]Analyse the effect of the donor's genetic polymorphism to dose normalized trough concentration of tacrolimus in liver transplant patients. Trough level of tacrolimus was adjusted by liver recipient's body weight.
Biospecimen Retention: Samples With DNA
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT03140462
|Contact: Fe-Lin Lin Wu||+886-2-3366 firstname.lastname@example.org|
|National Taiwan University Hospital||Not yet recruiting|
|Contact: Rey-Heng Hu|
|Principal Investigator:||Rey-Heng Hu||National Taiwan University Hospital|