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Trial record 72 of 1219 for:    arthritis+management

Ultrasound Utility in Routine Clinical Practise

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. Identifier: NCT03124225
Recruitment Status : Completed
First Posted : April 21, 2017
Last Update Posted : April 21, 2017
Information provided by (Responsible Party):
Barts & The London NHS Trust

Brief Summary:
The aim of this research study is to describe the impact of rheumatologist performed ultrasound on the diagnosis and management pathways of patients with rheumatoid arthritis. Primarily, to compare the time from first visit to treatment initiation between patients with and without rheumatologist-performed ultrasound assessment.

Condition or disease Intervention/treatment
Arthritis, Rheumatoid Ultrasonography Drug: DMARD

Detailed Description:

There are currently no guidelines for best practice in the use of ultrasound in RA and interim results from a survey by the British Society of Rheumatology (BSR) in this area have suggested that practice is variable across the UK. NICE recognize that the earlier persistent synovitis is identified and treated with disease modifying anti-rheumatic drugs DMARDs, the better the long term outcome and have welcomed the need to determine the role of imaging in assisting with this early diagnosis, and whether the added cost is justified by better disease outcomes.

This is a multi-site prospective observational study which investigates the use of ultrasound imaging in the context of patients with early arthritis presenting to secondary care. The time to commencement of DMARD therapy and diagnosis of Rheumatoid arthritis are therein outcome measures. Patients are followed up for 12 months after their first presentation and time to diagnosis or DMARD commencement recorded.

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Study Type : Observational
Actual Enrollment : 258 participants
Observational Model: Cohort
Time Perspective: Prospective
Official Title: The Impact of Rheumatologist-performed Ultrasound on Diagnosis and Management of Inflammatory Arthritis in Routine Clinical Practice
Study Start Date : June 2011
Actual Primary Completion Date : December 2012
Actual Study Completion Date : June 2013

Resource links provided by the National Library of Medicine

MedlinePlus related topics: Arthritis Ultrasound

Group/Cohort Intervention/treatment
Early Arthritis Patients seeing a Rheumatologist who uses US for assessment routinely in clinic
Early Arthritis Patients seeing a Rheumatologist who does not uses US for assessment routinely in clinic

Primary Outcome Measures :
  1. To compare the time from first visit to treatment initiation between patients with and without rheumatologist-performed ultrasound assessment [ Time Frame: 12 months ]

Information from the National Library of Medicine

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Ages Eligible for Study:   18 Years and older   (Adult, Older Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population
Early Arthritis patients

Inclusion Criteria:

  • Patients aged ≥18 years at the time of presentation to the clinic Patients newly presenting to the rheumatology clinic with suspected inflammatory arthritis

Exclusion Criteria:

  • For the non-ultrasound arm; patients who have been referred to another rheumatologist or radiologist for ultrasound Patients who decline or who are unable to consent to the use of their medical records for research

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Responsible Party: Barts & The London NHS Trust Identifier: NCT03124225     History of Changes
Other Study ID Numbers: IMM 09-0270
First Posted: April 21, 2017    Key Record Dates
Last Update Posted: April 21, 2017
Last Verified: September 2016

Additional relevant MeSH terms:
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Arthritis, Rheumatoid
Joint Diseases
Musculoskeletal Diseases
Rheumatic Diseases
Connective Tissue Diseases
Autoimmune Diseases
Immune System Diseases