Working…
ClinicalTrials.gov
ClinicalTrials.gov Menu

Oxytocin's Effect on Social Pain Empathy

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details.
 
ClinicalTrials.gov Identifier: NCT03122067
Recruitment Status : Unknown
Verified February 2018 by Keith Kendrick, University of Electronic Science and Technology of China.
Recruitment status was:  Recruiting
First Posted : April 20, 2017
Last Update Posted : February 7, 2018
Sponsor:
Information provided by (Responsible Party):
Keith Kendrick, University of Electronic Science and Technology of China

Brief Summary:
The aim of the present experiment is to examine oxytocin's behavioral and neural effects on social pain empathy

Condition or disease Intervention/treatment Phase
Healthy Drug: oxytocin treatment Drug: placebo treatment Not Applicable

Detailed Description:
In the current study, the investigators plan to examine whether oxytocin modulates behavior and neural activity during observing another person being excluded in an online ball-tossing game (a modified cyberball paradigm).

Layout table for study information
Study Type : Interventional  (Clinical Trial)
Estimated Enrollment : 60 participants
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Double (Participant, Investigator)
Primary Purpose: Basic Science
Official Title: Oxytocinergic Modulation of Perceived Social Exclusion
Actual Study Start Date : January 10, 2017
Estimated Primary Completion Date : October 30, 2018
Estimated Study Completion Date : October 30, 2018

Resource links provided by the National Library of Medicine

Drug Information available for: Oxytocin

Arm Intervention/treatment
Experimental: oxytocin group
male participants with oxytocin treatment
Drug: oxytocin treatment
intranasal administration of oxytocin

Placebo Comparator: placebo group
male participants with placebo treatment
Drug: placebo treatment
intranasal administration of placebo




Primary Outcome Measures :
  1. Neural activity changes associated with oxytocin administration [ Time Frame: 45-60 minutes after drug administration ]
    fMRI-assessed brain activity during observing other being socially excluded


Secondary Outcome Measures :
  1. Behavioral changes associated with oxytocin administration: ball-tossing [ Time Frame: 45-60 minutes after drug administration ]
    Number of tosses to the other players (the excluder, new player, or previously excluded player)



Information from the National Library of Medicine

Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies.


Layout table for eligibility information
Ages Eligible for Study:   18 Years to 30 Years   (Adult)
Sexes Eligible for Study:   Male
Accepts Healthy Volunteers:   Yes
Criteria

Inclusion Criteria:

  • healthy participants without past or current psychiatric or neurological disorders

Exclusion Criteria:

  • history of head injury
  • medical or psychiatric illness
  • smoking or drinking 24 hours before experiment

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT03122067


Contacts
Layout table for location contacts
Contact: Keith Kendrick, Dr. k.kendrick.uestc@gmail.com

Locations
Layout table for location information
China, Sichuan
School of Life Science and Technology, University of Electronic Science and Technology of China Recruiting
Chendu, Sichuan, China, 611731
Contact: Benjamin Becker, Dr.       ben_becker@gmx.de   
Sponsors and Collaborators
University of Electronic Science and Technology of China
Investigators
Layout table for investigator information
Principal Investigator: Keith Kendrick, Dr. School of Life Science and Technology, University of Electronic Science and Technology of China
Layout table for additonal information
Responsible Party: Keith Kendrick, Professor, University of Electronic Science and Technology of China
ClinicalTrials.gov Identifier: NCT03122067    
Other Study ID Numbers: UESTC-neuSCAN-33
First Posted: April 20, 2017    Key Record Dates
Last Update Posted: February 7, 2018
Last Verified: February 2018

Layout table for additional information
Studies a U.S. FDA-regulated Drug Product: No
Studies a U.S. FDA-regulated Device Product: No
Keywords provided by Keith Kendrick, University of Electronic Science and Technology of China:
oxytocin
social cognition
fMRI
empathy
Additional relevant MeSH terms:
Layout table for MeSH terms
Oxytocin
Oxytocics
Reproductive Control Agents
Physiological Effects of Drugs