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The Study of Sarcopenia and Aging Biomarkers by the Metabolomics

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ClinicalTrials.gov Identifier: NCT03121326
Recruitment Status : Unknown
Verified March 2017 by Chang Gung Memorial Hospital.
Recruitment status was:  Recruiting
First Posted : April 20, 2017
Last Update Posted : May 19, 2017
Sponsor:
Collaborator:
Chang Gung University
Information provided by (Responsible Party):
Chang Gung Memorial Hospital

Brief Summary:
With the rapid growth of the global elderly population, the studies of the biomarkers of the sarcopenia and aging are under investigation in different ways. The investigators use Metabolomics to explore the biomarkers of the sarcopenia and aging of the senior adults.

Condition or disease Intervention/treatment
Sarcopenia Aging Diagnostic Test: blood and urine sampling

Detailed Description:
Metabolomics is the emerging platform technology to address the complexity of a living system. In translational research, metabolomics approaches may enable the detection of multiple disease risk factors and interactions, disease progression, and response of patients to a particular therapy with or without side effects. Metabolomics may provide comprehensive information and improve diagnosis and prognosis which are particularly promising in human complex degenerative diseases. The investigators use Metabolomics to explore the biomarkers of the sarcopenia and aging of the senior adults.

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Study Type : Observational
Estimated Enrollment : 650 participants
Observational Model: Cohort
Time Perspective: Prospective
Official Title: The Study of Sarcopenia and Aging Biomarkers by the Metabolomics
Actual Study Start Date : March 6, 2017
Actual Primary Completion Date : March 15, 2017
Estimated Study Completion Date : December 31, 2017

Resource links provided by the National Library of Medicine



Intervention Details:
  • Diagnostic Test: blood and urine sampling
    Ten mL blood and 15mL urine are collected.


Primary Outcome Measures :
  1. The biomarkers of the sarcopenia and aging in senior adults. [ Time Frame: one year ]
    Metabolomics to explore the biomarkers of the sarcopenia and aging.


Biospecimen Retention:   Samples Without DNA
blood and urine


Information from the National Library of Medicine

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Ages Eligible for Study:   60 Years and older   (Adult, Older Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes
Sampling Method:   Non-Probability Sample
Study Population
650 residents of the Chang Gung Health and Culture Village aged over 60.
Criteria

Inclusion Criteria:

  • residents of the Chang Gung Health and Culture Village
  • mostly independent and do not require nursing assistance
  • capable of managing their daily living activities
  • aged ≧ 60

Exclusion Criteria:


Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT03121326


Contacts
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Contact: Chih-Ming Lin, M.D. 886-975362603 lin789@adm.cgmh.org.tw

Locations
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Taiwan
Chang Gung University Recruiting
Taoyuan, Taiwan, 333
Contact: Mei-Ling Cheng, PhD    886-3-2118800 ext 3650    chengm@mail.cgu.edu.tw   
Sponsors and Collaborators
Chang Gung Memorial Hospital
Chang Gung University
Investigators
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Study Chair: Chih-Ming Lin, M.D. Chang Gung Memorial Hospital
Principal Investigator: Mei-Ling Cheng, PhD Chang Gung University

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Responsible Party: Chang Gung Memorial Hospital
ClinicalTrials.gov Identifier: NCT03121326     History of Changes
Other Study ID Numbers: 201700245B0
First Posted: April 20, 2017    Key Record Dates
Last Update Posted: May 19, 2017
Last Verified: March 2017
Individual Participant Data (IPD) Sharing Statement:
Plan to Share IPD: Undecided

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Studies a U.S. FDA-regulated Drug Product: No
Studies a U.S. FDA-regulated Device Product: No

Keywords provided by Chang Gung Memorial Hospital:
Sarcopenia
Aging
Biomarkers
Metabolomics

Additional relevant MeSH terms:
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Sarcopenia
Muscular Atrophy
Neuromuscular Manifestations
Neurologic Manifestations
Nervous System Diseases
Atrophy
Pathological Conditions, Anatomical
Signs and Symptoms