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Lung Ultrasound in High Altitude Lung Edema

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ClinicalTrials.gov Identifier: NCT03117686
Recruitment Status : Completed
First Posted : April 18, 2017
Last Update Posted : December 2, 2017
Sponsor:
Information provided by (Responsible Party):
Ulrike Weber, Medical University of Vienna

Brief Summary:
High altitude pulmonary edema is a life-threatening condition that remains a concern for climbers and clinicians alike. It is defined as a non-cardiac pulmonary edema occurring at altitudes exceeding 3000m in non-acclimatised individuals. Recently, studies conducted in remote areas have demonstrated that ultrasound lung comets (B lines) can be used as a measure of sub-acute pulmonary edema and high altitude pulmonary edema in climbers ascending to altitude. the investigators want to assess the occurrence of of comet tails (B lines) as a measure of pulmonary edema among patients after lung transplantation and healthy individuals during an expedition to Mount Kilimanjaro.

Condition or disease Intervention/treatment
Pulmonary Edema Diagnostic Test: lung ultrasound

  Show Detailed Description

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Study Type : Observational
Actual Enrollment : 20 participants
Observational Model: Other
Time Perspective: Prospective
Official Title: Estimation of Pulmonary Arterial Pressure With Transesophageal Echocardiography: A Pilot Study
Actual Study Start Date : June 10, 2017
Actual Primary Completion Date : June 22, 2017
Actual Study Completion Date : November 30, 2017

Resource links provided by the National Library of Medicine


Group/Cohort Intervention/treatment
healthy volunteers
10 healthy volunteers climbing Mount Kilimanjaro receiving lung ultrasound
Diagnostic Test: lung ultrasound
lung ultrasound with positive "B-line pattern" in patients after lung transplantations and healthy volunteers at sea level and high altitude (4600 m) at Mountb Kilimanjaro

patients after lung transplantation
10 patients > 2years after lung transplantation climbing Mount Kilimanjaro receiving lung ultrasound
Diagnostic Test: lung ultrasound
lung ultrasound with positive "B-line pattern" in patients after lung transplantations and healthy volunteers at sea level and high altitude (4600 m) at Mountb Kilimanjaro




Primary Outcome Measures :
  1. lung ultrasound [ Time Frame: 2 weeks ]
    Positive "B-line pattern" in patients after lung transplantations and healthy volunteers at sea level and high altitude (4600 m)


Secondary Outcome Measures :
  1. optic nerve sheath diameter [ Time Frame: 2 weeks ]
    optic nerve sheath diameter in patients after lung transplantations and healthy volunteers at sea level and high altitude (4600 m)



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Ages Eligible for Study:   18 Years to 99 Years   (Adult, Older Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes
Sampling Method:   Probability Sample
Study Population
10 patients > 2 years after lung transplantation and 10 healthy volunteers during expedition to Mount Kilimanjaro
Criteria

Inclusion Criteria:

  • Expedition to Mount Kilimanjaro

Exclusion Criteria:

  • Refusal to participate in the study
  • Age < 18 years

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT03117686


Locations
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Austria
Medical university of vienna, General hospital of Vienna
Vienna, Austria, 1090
Sponsors and Collaborators
Medical University of Vienna
Investigators
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Principal Investigator: Ulrike Weber, M.D. Medical University of Vienna

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Responsible Party: Ulrike Weber, Ass.Prof.Dr., Medical University of Vienna
ClinicalTrials.gov Identifier: NCT03117686     History of Changes
Other Study ID Numbers: 1236/2017
First Posted: April 18, 2017    Key Record Dates
Last Update Posted: December 2, 2017
Last Verified: November 2017
Individual Participant Data (IPD) Sharing Statement:
Plan to Share IPD: No

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Studies a U.S. FDA-regulated Drug Product: No
Studies a U.S. FDA-regulated Device Product: No
Additional relevant MeSH terms:
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Pulmonary Edema
Edema
Signs and Symptoms
Lung Diseases
Respiratory Tract Diseases