ClinicalTrials.gov
ClinicalTrials.gov Menu

Workload of Water Polo Players Following a Phosphorus Manipulated High Carbohydrate Meal

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Know the risks and potential benefits of clinical studies and talk to your health care provider before participating. Read our disclaimer for details.
ClinicalTrials.gov Identifier: NCT03101215
Recruitment Status : Recruiting
First Posted : April 5, 2017
Last Update Posted : April 5, 2017
Sponsor:
Information provided by (Responsible Party):
Omar Obeid, American University of Beirut Medical Center

Brief Summary:
Phosphorus is a widely used sport supplement. Most athletes who use it follow a phosphorus loading approach which consists of a weeklong phosphorus intake of 3-4 gr per day for optimal effect. The ergogenic potential of phosphorus is believed to be related to several factors including its ability to a) enhance ATP availability for energy expenditure and b) increase plasma content of 2.3-DPG (2.3-disphosphoglycerate) that is known to reduce oxygen affinity to hemoglobin and consequently enhances its release in the exercising tissue. Additionally, phosphorus was reported to increase peripheral glucose uptake and thus glycogenesis and glycogen storage. We have recently observed that the peripheral glucose uptake was stimulated by co-ingestion of phosphorus with meal, while pre ingestion failed to do so. Thus it is reasonable to postulate that phosphorus co-ingestion with meal improves ergogenesis through enhancing glycogen storage. The aim of this experiment is to investigate whether acute phosphate supplementation of a glucose load is responsible for the performance enhancement. This may help in explaining the controversies surrounding the impact of phosphorus on performance. A cross over study will be conducted on water polo players. In brief, overnight fasted subjects, will be given glucose load with or without phosphorus. Three hours later their performance will be measured using an ergometer cycling machine.

Condition or disease Intervention/treatment Phase
Energy Expenditure Dietary Supplement: phosphorus Not Applicable

  Show Detailed Description

Study Type : Interventional  (Clinical Trial)
Estimated Enrollment : 17 participants
Allocation: Randomized
Intervention Model: Crossover Assignment
Masking: Double (Participant, Investigator)
Primary Purpose: Basic Science
Official Title: Workload of Water Polo Players Following a Phosphorus Manipulated High Carbohydrate Meal
Actual Study Start Date : March 24, 2017
Estimated Primary Completion Date : March 24, 2018
Estimated Study Completion Date : March 24, 2018

Resource links provided by the National Library of Medicine

MedlinePlus related topics: Drinking Water
Drug Information available for: Phosphorus

Arm Intervention/treatment
Placebo Comparator: Placebo
glucose drink (100g) with placebo tablets
Dietary Supplement: phosphorus
adding of phosphorus to high carbohydrate meal

Active Comparator: phosphorus
Glucose drink (100g) with phosphorus tablets (400 mg of phosphorus)
Dietary Supplement: phosphorus
adding of phosphorus to high carbohydrate meal




Primary Outcome Measures :
  1. workload or performance enhancement or METs [ Time Frame: up to 40 min ]
    power (watt) and time to exhaustion



Information from the National Library of Medicine

Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies.


Ages Eligible for Study:   18 Years to 25 Years   (Adult)
Sexes Eligible for Study:   Male
Gender Based Eligibility:   Yes
Accepts Healthy Volunteers:   Yes
Criteria

Inclusion Criteria:

  • water polo player

Exclusion Criteria:


Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT03101215


Contacts
Contact: Omar Obeid, PhD 00961 1 350000 ext 4440 oo01@aub.edu.lb

Locations
Lebanon
American University of Beirut Recruiting
Beirut, Lebanon
Contact: Omar Obeid, PhD         
Sponsors and Collaborators
American University of Beirut Medical Center
Investigators
Principal Investigator: omar obeid, PhD American University of Beirut Medical Center

Publications:

Responsible Party: Omar Obeid, Professor, American University of Beirut Medical Center
ClinicalTrials.gov Identifier: NCT03101215     History of Changes
Other Study ID Numbers: NUT:OO:24
First Posted: April 5, 2017    Key Record Dates
Last Update Posted: April 5, 2017
Last Verified: April 2017
Individual Participant Data (IPD) Sharing Statement:
Plan to Share IPD: No

Studies a U.S. FDA-regulated Drug Product: No
Studies a U.S. FDA-regulated Device Product: No