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Trial record 1 of 1 for:    NCT03082326
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The CCUS Based Characteristic of Hemodynamic and Lung Pathology in Early Stage of Shock in ICU: The Epidemic and Prognostic Value

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ClinicalTrials.gov Identifier: NCT03082326
Recruitment Status : Completed
First Posted : March 17, 2017
Last Update Posted : August 1, 2017
Sponsor:
Information provided by (Responsible Party):
tongjuan ZOU, West China Hospital

Brief Summary:
Shock is a common condition in critical care unit (ICU). It is extremely important that the patient accepts early goal-directed therapy (EGDT) treatment in the early stage of shock. However, several studies failed to demonstrate that the well used variables such as CVP and others could direct to a better treatment. In recent years, critical care ultrasound (CCUS) has been respected as a reliable noninvasive tool and widely used in ICU practice. With CCUS the investigators can accurately acquired the detailed information of the characteristic of the hemodynamics and lung pathology (the systole and diastole function, volume status, valve insufficiency, lung, edema, consolidation, and pleural effusion, etc.). To the investigators knowledge, there is no study investigating the epidemic of such ultrasonic variables and its value to predict to outcome. The aim of this study is to investigate the epidemic and the prognostic value of CCUS Based Characteristic of Hemodynamic and Lung pathology in Early Stage of Shock in patients admitted in ICU.

Condition or disease
Shock

Detailed Description:
Adult patients who admitted to the intensive care unit of West China hospital of sichuan university with shock from April 2016 to April 2017 enrolled.

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Study Type : Observational
Actual Enrollment : 181 participants
Observational Model: Other
Time Perspective: Prospective
Official Title: The Critical Care Ultrasound Based Characteristic of Hemodynamic and Lung Pathology in Early Stage of Shock in ICU: The Epidemic and Prognostic Value
Study Start Date : April 5, 2016
Actual Primary Completion Date : June 6, 2017
Actual Study Completion Date : June 6, 2017

Resource links provided by the National Library of Medicine

MedlinePlus related topics: Critical Care Shock




Primary Outcome Measures :
  1. all cause mortality [ Time Frame: 28 days ]

Secondary Outcome Measures :
  1. length of mechanical ventilation [ Time Frame: through study completion, an average of 28 days ]
  2. ICU length of stay [ Time Frame: through study completion, an average of 28 days ]
  3. hospital length of stay [ Time Frame: through study completion, an average of 28 days ]


Information from the National Library of Medicine

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Ages Eligible for Study:   18 Years and older   (Adult, Older Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population
Shock patients with 6 hours admitted in ICU in west china hospital of sichuan university.
Criteria

Inclusion Criteria:

  1. SBP<90 mm Hg or MAP <70 mm Hg or SBP decrease >40mmHg or need vasoactive drugs;
  2. Skin that is cold and clammy, capillary refill time >4.5s, urine output of <0.5ml/Kg.hr and lactate>2mmol/L;
  3. SHOCK presented within 6 hr.

Exclusion Criteria:

  1. <18 years old;
  2. Pregnancy;
  3. Patient or family member refuse to be enrolled.

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT03082326


Locations
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China, Sichuan
West China Hospital,Sichuan University
Chengde, Sichuan, China, 610041
Sponsors and Collaborators
West China Hospital
Investigators
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Study Chair: yan kang, doctor West China Hospital
Publications of Results:
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Responsible Party: tongjuan ZOU, Doctor, West China Hospital
ClinicalTrials.gov Identifier: NCT03082326    
Other Study ID Numbers: West China H
First Posted: March 17, 2017    Key Record Dates
Last Update Posted: August 1, 2017
Last Verified: March 2017
Individual Participant Data (IPD) Sharing Statement:
Plan to Share IPD: No

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Studies a U.S. FDA-regulated Drug Product: No
Studies a U.S. FDA-regulated Device Product: No
Keywords provided by tongjuan ZOU, West China Hospital:
shock
critical care ultrasound
hemodynamics
lung pathology
epidemic
prognosis
Additional relevant MeSH terms:
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Shock
Pathologic Processes