Changes in Plasma Osmolality Related to the Use of Cardiopulmonary Bypass With Hyperosmolar Prime.
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|ClinicalTrials.gov Identifier: NCT03060824|
Recruitment Status : Completed
First Posted : February 23, 2017
Last Update Posted : December 15, 2017
|Condition or disease||Intervention/treatment|
|Cardiopulmonary Bypass||Other: Blood sampling|
|Study Type :||Observational|
|Actual Enrollment :||30 participants|
|Official Title:||Changes in Plasma Osmolality Related to the Use of Cardiopulmonary Bypass With Hyperosmolar Prime, an Observational Study.|
|Actual Study Start Date :||February 21, 2017|
|Actual Primary Completion Date :||December 11, 2017|
|Actual Study Completion Date :||December 11, 2017|
CABG with the aid of CPB.
Cardiac surgical patients subjected to coronary artery bypass grafting with the aid of Cardiopulmonary Bypass. Perioperative measurements of osmolality in plasma.
Other: Blood sampling
To explore changes in osmolality during coronary artery bypass grafting surgery with the aid of Cardiopulmonary Bypass by repeated measurements of osmolality and concentration shifts of sodium, glucose and urea in plasma.
- Changes in plasma osmolality [ Time Frame: Before surgery; repeated during surgery and on postoperative day 1 and 2. ]Repeated measurements of plasma osmolality aim to outline changes in plasma osmolality related to the use of hyperosmolar prime.
- Change in osmolar gap [ Time Frame: Before surgery; repeated during surgery and on postoperative day 1 and 2. ]Analysing urea, sodium and glucose in plasma using the same sampling intervals as for plasma osmolality enables calculation of the osmolar gap and to set its relation to the use of hyperosmolar prime
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Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT03060824
|Heart Centre, Umeå University Hospital|
|Umeå, Sweden, SE 901 85|
|Principal Investigator:||Magnus Hedström, MD||Heart Centre, Umeå University Hospital, Sweden|