PREdicting RENAL Injury In Patient After Hip Fracture Surgery (PRE-RENAL)
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|ClinicalTrials.gov Identifier: NCT03049150|
Recruitment Status : Not yet recruiting
First Posted : February 9, 2017
Last Update Posted : February 9, 2017
|Condition or disease|
|Acute Kidney Injury|
The PRE-RENAL study is a prognostic accuracy study testing the ability of the MALDI-MS assay to predict incident acute kidney injury after fractured neck of femur surgery. The study aims to validate the findings of a urinary peptide panel previously developed and validated on a cohort of septic patients.
Kidney injury following surgery or as a part of severe illness is an important complication, because it can delay and reduce the chances of recovery. A reliable early test for kidney injury would be useful so that treatments to prevent or minimise it can be started as early as possible. This study, based with a group of medical researchers working with chemists, will analyse clinical urine specimens from patients undergoing major orthopaedic (bone) surgery. We will explore whether patterns of proteins in the urine could be used as an early warning that kidney injury is present before existing tests demonstrate it.
|Study Type :||Observational|
|Estimated Enrollment :||20 participants|
|Official Title:||The Use of Urinary MALDI-MS in Predicting Post-Operative Acute Kidney Injury in Patients After Fixation of Fractured Neck of Femur.|
|Estimated Study Start Date :||February 2017|
|Estimated Primary Completion Date :||April 2017|
|Estimated Study Completion Date :||June 2017|
- Acute Kidney Injury [ Time Frame: Within 7 days ]Defined by KDIGO Criteria
Biospecimen Retention: Samples Without DNA
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT03049150
|Contact: Tim Walsh, MDfirstname.lastname@example.org|