Children-Adult Asthma Cohort Study in China
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|ClinicalTrials.gov Identifier: NCT03046433|
Recruitment Status : Not yet recruiting
First Posted : February 8, 2017
Last Update Posted : May 9, 2017
|Condition or disease|
|Asthma in Children|
Asthma is one of the most common chronic diseases all over the world. GINA (Global Initiative for Asthma) reported that nearly 300 million were diagnosed with asthma, while in China even reach to 30 million. In recent years, the prevalence of pediatric asthma and severe cases in China has increased considerably. In 2013, the third national survey carried out in 43 cities in 27 provinces and found that asthma prevalence among children aged 0-14 years old reached to 3.02%, with the highest prevalence in Shanghai (7.57%), while in year of 2000, the rat was 1.09%. However, the research about mechanism, risk factors, individualized prevention and treatment strategy of asthma in China is still not perfect and there is no basic data and multicenter cohort study. Therefore, this multicenter cohort study is conducted, in order to set up a complete database, biobank and long term follow up of Chinese children, and establish foundations for basic research and precise medicine.
Pediatric patients more than or equal to 6 years old diagnosed with asthma will be recruited in this study. After evaluating the baseline, the patients were followed up. Visiting doctors and filling in a questionnaire for every three months, the clinical symptoms, physical examination, will be detected. Chest X ray, blood tests, lung function test and FeNO test would be done when necessary. And, biological samples of blood, urine and throat swab will be collected when recruiting and finishing follow-up. The trial will be completed in 60 months, with 4000 subjects recruited from 8 hospitals.
|Study Type :||Observational|
|Estimated Enrollment :||4000 participants|
|Official Title:||Children-Adult Asthma Cohort Study in China|
|Estimated Study Start Date :||June 2017|
|Estimated Primary Completion Date :||March 2022|
|Estimated Study Completion Date :||December 2022|
- Long-term changes on lung function of Chinese children with asthma when treated according to GINA guideline [ Time Frame: 60 months ]
- Asthma Quality of Life Questionnaire with Standardized Activities [ Time Frame: 3 months ]
- Asthma Control Questionnaire [ Time Frame: 3 months ]
- Frequencies of acute attack of asthma in children [ Time Frame: 60 months ]Times of acute asthmatic attack will be recorded every year from baseline to 60 months, assessed by questionnaire.
- Complications of children with pediatric asthma [ Time Frame: 60 months ]
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT03046433
|Contact: Baoping Xu, MD,PhDfirstname.lastname@example.org|
|Contact: Kunling Shen, Study Principal Investigator|