Catheter Ablation of Arrhythmias to Improve CRT Response (ABLATE-CRT)
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|ClinicalTrials.gov Identifier: NCT03035227|
Recruitment Status : Terminated (Investigator left Institution.)
First Posted : January 27, 2017
Last Update Posted : May 23, 2018
|Condition or disease||Intervention/treatment||Phase|
|Arrhythmia, Cardiac||Procedure: Catheter Ablation Drug: Anti-Arrhythmics||Phase 4|
|Study Type :||Interventional (Clinical Trial)|
|Actual Enrollment :||2 participants|
|Intervention Model:||Parallel Assignment|
|Masking:||None (Open Label)|
|Official Title:||Catheter Ablation of Arrhythmias to Improve CRT Response|
|Actual Study Start Date :||January 23, 2017|
|Actual Primary Completion Date :||May 1, 2018|
|Actual Study Completion Date :||May 1, 2018|
Active Comparator: Catheter Ablation
Catheter ablation procedure of atrial and/or ventricular arrhythmias.
Procedure: Catheter Ablation
Catheter ablation of atrial or ventricular arrhythmia. The technique and type of ablation will be at the discretion of the treating electrophysiologists.
Active Comparator: Medical Therapy
Medical management using antiarrhythmic drugs per standard of care of treating physician.
Anti-Arrhythmic drugs that are deemed to be appropriate for the given participants's arrhythmia by the treating physician.
- Change in Ejection Fraction (EF) [ Time Frame: 90 Days ]
- Bi-ventricular pacing improvement [ Time Frame: 90 Days ]
- Cardiovascular mortality [ Time Frame: 365Days ]
- All-cause mortality [ Time Frame: 365 Days ]
- Hospital admissions for heart failure exacerbation [ Time Frame: 365 Days ]
- New York Heart Association (NYHA) class change [ Time Frame: 30 Days ]
- Change in 6 minute walk test [ Time Frame: 30 Days ]
- Change in Quality of Life - SF-36 [ Time Frame: 30 Days ]
- Change in Quality of Life Kansas City Cardiomyopathy Questionnaire (KCCQ) [ Time Frame: 30 Days ]
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT03035227
|United States, Kansas|
|University of Kansas Medical Center|
|Kansas City, Kansas, United States, 66160|
|Principal Investigator:||Dhanunjaya Lakkireddy, MD||University of Kansas Medical Center|