We updated the design of this site on December 18, 2017. Learn more.
ClinicalTrials.gov
ClinicalTrials.gov Menu

The Difference Seen in Granulosa Cells and Immature Oocytes in IVF Treated Patients Sorted by Body Mass Index (BMI)

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Know the risks and potential benefits of clinical studies and talk to your health care provider before participating. Read our disclaimer for details.
ClinicalTrials.gov Identifier: NCT03020173
Recruitment Status : Not yet recruiting
First Posted : January 13, 2017
Last Update Posted : January 13, 2017
Sponsor:
Information provided by (Responsible Party):
Hillel Yaffe Medical Center

Brief Summary:
This study aims to discover the connection between BMI and oocyte and granulosa consistencies.

Condition or disease Intervention/treatment
Infertility, Female Other: Laboratory study

Study Type : Observational
Estimated Enrollment : 100 participants
Observational Model: Case Control
Time Perspective: Prospective
Study Start Date : January 2017
Estimated Primary Completion Date : January 2018
Estimated Study Completion Date : July 2018

Resource links provided by the National Library of Medicine

U.S. FDA Resources

Group/Cohort Intervention/treatment
BMI above 30
Oocytes and granulosa of infertile women with BMI above 30
Other: Laboratory study
Laboratory analysis to determine composition of granulosa and oocytes
BMI below 30
Oocytes and granulosa of infertile women with BMI above 30
Other: Laboratory study
Laboratory analysis to determine composition of granulosa and oocytes



Primary Outcome Measures :
  1. Measurement of composition of granulosa cells and oocytes [ Time Frame: One year ]
    Laboratory measurement of lipid and cholesterol amounts, mitochondrial distribution and telomere length according to BMI levels



Information from the National Library of Medicine

Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies.


Ages Eligible for Study:   18 Years to 45 Years   (Adult)
Sexes Eligible for Study:   Female
Accepts Healthy Volunteers:   No
Sampling Method:   Probability Sample
Study Population
Infertile women undergoing IVF treatment
Criteria

Inclusion Criteria:

  • Infertile women undergoing IVF
  • Consent to participate in study

Exclusion Criteria:

  • Fertility preservation due to cancer
  • Endocrine disorders

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT03020173


Contacts
Contact: Rinat Lift, MSc rinatl@hy.health.gov.il
Contact: Shira Raviv, MD drshiraraviv@gmail.com

Sponsors and Collaborators
Hillel Yaffe Medical Center

Responsible Party: Hillel Yaffe Medical Center
ClinicalTrials.gov Identifier: NCT03020173     History of Changes
Other Study ID Numbers: HYMC-0098-16
First Posted: January 13, 2017    Key Record Dates
Last Update Posted: January 13, 2017
Last Verified: January 2017
Individual Participant Data (IPD) Sharing Statement:
Plan to Share IPD: No

Additional relevant MeSH terms:
Infertility
Infertility, Female
Genital Diseases, Male
Genital Diseases, Female