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Bed Rest, Inactivity and Early Responses (BIER)

This study is currently recruiting participants.
Verified November 2016 by University of Exeter
Sponsor:
ClinicalTrials.gov Identifier:
NCT02981927
First Posted: December 5, 2016
Last Update Posted: December 5, 2016
The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Know the risks and potential benefits of clinical studies and talk to your health care provider before participating. Read our disclaimer for details.
Information provided by (Responsible Party):
University of Exeter
  Purpose
To evaluate the early metabolic responses (whole body and within muscle tissue) to a single day of whole body physical inactivity (i.e. bed-rest), and evaluate the contribution of inactivity per se vs alterations in diet

Condition Intervention
Metabolic Responses to Inactivity Other: Physical inactivity

Study Type: Interventional
Study Design: Allocation: Randomized
Intervention Model: Crossover Assignment
Masking: None (Open Label)
Primary Purpose: Basic Science
Official Title: Bed Rest, Inactivity and Early Responses

Further study details as provided by University of Exeter:

Primary Outcome Measures:
  • Glucose tolerance [ Time Frame: 24 hours ]

Estimated Enrollment: 10
Study Start Date: January 2015
Estimated Study Completion Date: December 2017
Estimated Primary Completion Date: January 2017 (Final data collection date for primary outcome measure)
Arms Assigned Interventions
No Intervention: Control
24 h habitual physical activity fed in energy balance
Experimental: Bed rest matched diet
24 hour period of whole body bed-rest with a matched diet
Other: Physical inactivity
Experimental: Bed rest balanced diet
24 hour period of whole body bed-rest fed in energy balance
Other: Physical inactivity

  Eligibility

Information from the National Library of Medicine

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Ages Eligible for Study:   18 Years to 40 Years   (Adult)
Sexes Eligible for Study:   Male
Accepts Healthy Volunteers:   Yes
Criteria

Inclusion Criteria:

  • Healthy and aged 18-40 y
  • BMI between 18 and 30

Exclusion Criteria:

  • On medication
  • Family history of metabolic disease
  • Diagnosed with any metabolic or cardiovascular conditions
  • BMI < 18 or > 30
  Contacts and Locations
Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT02981927


Contacts
Contact: Benjamin T Wall, PhD +441392724774 ext 4774 b.t.wall@exeter.ac.uk

Locations
United Kingdom
Sport & Health Sciences Recruiting
Exeter, Devon, United Kingdom, EX1 2LU
Contact: Benjamin T Wall, PhD    +441392 724774 ext 4774    b.t.wall@exeter.ac.uk   
Sponsors and Collaborators
University of Exeter
  More Information

Responsible Party: University of Exeter
ClinicalTrials.gov Identifier: NCT02981927     History of Changes
Other Study ID Numbers: 157758/02
First Submitted: November 30, 2016
First Posted: December 5, 2016
Last Update Posted: December 5, 2016
Last Verified: November 2016
Individual Participant Data (IPD) Sharing Statement:
Plan to Share IPD: No