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Bed Rest, Inactivity and Early Responses (BIER)

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ClinicalTrials.gov Identifier: NCT02981927
Recruitment Status : Completed
First Posted : December 5, 2016
Last Update Posted : May 25, 2018
Sponsor:
Information provided by (Responsible Party):
University of Exeter

Brief Summary:
To evaluate the early metabolic responses (whole body and within muscle tissue) to a single day of whole body physical inactivity (i.e. bed-rest), and evaluate the contribution of inactivity per se vs alterations in diet

Condition or disease Intervention/treatment Phase
Metabolic Responses to Inactivity Other: Physical inactivity Not Applicable

Study Type : Interventional  (Clinical Trial)
Actual Enrollment : 10 participants
Allocation: Randomized
Intervention Model: Crossover Assignment
Masking: None (Open Label)
Primary Purpose: Basic Science
Official Title: Bed Rest, Inactivity and Early Responses
Study Start Date : January 2015
Actual Primary Completion Date : December 2, 2016
Actual Study Completion Date : December 2, 2016

Arm Intervention/treatment
No Intervention: Control
24 h habitual physical activity fed in energy balance
Experimental: Bed rest matched diet
24 hour period of whole body bed-rest with a matched diet
Other: Physical inactivity
Experimental: Bed rest balanced diet
24 hour period of whole body bed-rest fed in energy balance
Other: Physical inactivity



Primary Outcome Measures :
  1. Glucose tolerance [ Time Frame: 24 hours ]


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Ages Eligible for Study:   18 Years to 40 Years   (Adult)
Sexes Eligible for Study:   Male
Accepts Healthy Volunteers:   Yes
Criteria

Inclusion Criteria:

  • Healthy and aged 18-40 y
  • BMI between 18 and 30

Exclusion Criteria:

  • On medication
  • Family history of metabolic disease
  • Diagnosed with any metabolic or cardiovascular conditions
  • BMI < 18 or > 30

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT02981927


Locations
United Kingdom
Sport & Health Sciences
Exeter, Devon, United Kingdom, EX1 2LU
Sponsors and Collaborators
University of Exeter

Responsible Party: University of Exeter
ClinicalTrials.gov Identifier: NCT02981927     History of Changes
Other Study ID Numbers: 157758/02
First Posted: December 5, 2016    Key Record Dates
Last Update Posted: May 25, 2018
Last Verified: May 2018
Individual Participant Data (IPD) Sharing Statement:
Plan to Share IPD: No