Detection of Group A Streptococcus (GAS) in Oral Cavity

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Read our disclaimer for details. Identifier: NCT02972437
Recruitment Status : Unknown
Verified November 2016 by Hadassah Medical Organization.
Recruitment status was:  Not yet recruiting
First Posted : November 23, 2016
Last Update Posted : November 29, 2016
Information provided by (Responsible Party):
Hadassah Medical Organization

Brief Summary:
The investigators intend to screen children who are suspected of having GAS tonsillitis. From each child we will take a throat culture and saliva sample to screen for molecular evidence of GAS.

Condition or disease Intervention/treatment
Tonsillitis Other: sample taking

Study Type : Observational
Estimated Enrollment : 100 participants
Observational Model: Cohort
Time Perspective: Prospective
Official Title: Detection of Group A Streptococcus (GAS) in Oral Cavity Using Molecular Techniques
Study Start Date : December 2016
Estimated Primary Completion Date : December 2017
Estimated Study Completion Date : January 2018

Resource links provided by the National Library of Medicine

MedlinePlus related topics: Tonsillitis

Intervention Details:
  • Other: sample taking
    throat culture and oral cavity sample

Primary Outcome Measures :
  1. molecular detection of GAS compared to throat culture detection [ Time Frame: 3 days ]
    3 days after taking the oral sample, the investigators will compare it to the throat culture taken at the same time.

Information from the National Library of Medicine

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Ages Eligible for Study:   3 Years to 16 Years   (Child)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Sampling Method:   Non-Probability Sample
Study Population
children 3-16 years old with evidence of tonsilitis

Inclusion Criteria:

  • clinical evidence of GAS tonsillitis
  • healthy, no chronic illness
  • not a GAS carrier

Exclusion Criteria:

  • GAS carrier
  • Active background disease

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its identifier (NCT number): NCT02972437

Contact: saar hashavya, doctor 972 53 223 3987
Contact: naama shwartz, doctor 972545216158

Sponsors and Collaborators
Hadassah Medical Organization

Responsible Party: Hadassah Medical Organization Identifier: NCT02972437     History of Changes
Other Study ID Numbers: naamap-HMO-CTIL
First Posted: November 23, 2016    Key Record Dates
Last Update Posted: November 29, 2016
Last Verified: November 2016
Individual Participant Data (IPD) Sharing Statement:
Plan to Share IPD: No

Keywords provided by Hadassah Medical Organization:
GAS in oral cavity

Additional relevant MeSH terms:
Pharyngeal Diseases
Stomatognathic Diseases
Respiratory Tract Infections
Respiratory Tract Diseases
Otorhinolaryngologic Diseases