Mouthwash of Pomegranate Against Biofilm and Gingival Inflammation in School Children
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|ClinicalTrials.gov Identifier: NCT02949583|
Recruitment Status : Completed
First Posted : October 31, 2016
Last Update Posted : October 31, 2016
|Condition or disease||Intervention/treatment||Phase|
|Gingivitis||Drug: Punica granatum Linn. Drug: chlorhexidine||Not Applicable|
|Study Type :||Interventional (Clinical Trial)|
|Actual Enrollment :||35 participants|
|Intervention Model:||Parallel Assignment|
|Masking:||Double (Participant, Investigator)|
|Official Title:||Clinical Effectiveness and Microbiological Evaluation of a Mouthwash of Pomegranate (Punica Granatum Linn.) in School Children|
|Study Start Date :||March 2012|
|Actual Primary Completion Date :||May 2012|
|Actual Study Completion Date :||May 2012|
Experimental: Punica granatum Linn.
The childrens used the mouthwash contain pomegranate 6,25% twice daily for 14 days.
Drug: Punica granatum Linn.
Mouthwash (6,25% of Punica granatum Linn) 10mL per day during 14 days
Other Name: Pomegranate
Active Comparator: chlorhexidine
The childrens used the mouthwash contain chlorhexidine 0.12% twice daily for 14 days.
standard anti-bacterial mouthwash Mouthwash (0,12% chlorhexidine) 10mL per day during 14 days
Other Name: Periogard
- Difference in the Gingival Index scores. [ Time Frame: Baseline, Seventh Day and Fourteeth day (14 days) ]On day 0, we measured the Plaque Index (PI) (Silness; Löe, 1964) at baseline, on the seventh day and on the fourteenth day.
- Difference in the Gingival Bleeding Index scores. [ Time Frame: Baseline, Seventh Day andFourteeth day (14 days) ]On day 0, we measured the Bleeding on Probing Index (BPI) (Ainamo; Bay, 1975) at baseline, on the seventh day and on the fourteenth day.
- Difference in the Microbiological analysis of saliva for oral streptococcus count evolution from the start till the end of the study. [ Time Frame: Baseline and Fourteeth day (14 days) ]At baseline, we collected non-stimulated saliva samples into a sterile container for counting of oral streptococci in the laboratory. And on the fourteenth day, we carried out the second saliva collection and measured the clinical indices used.
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Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT02949583
|Universidade Estadual Da Paraiba|
|Campina Grande, Paraiba, Brazil, 58.429-500|
|Principal Investigator:||DANÚBIA RM NÓBREGA, Mastering||Universidade Estadual da Paraiba|