Mouthwash of Pomegranate Against Biofilm and Gingival Inflammation in School Children
|ClinicalTrials.gov Identifier: NCT02949583|
Recruitment Status : Completed
First Posted : October 31, 2016
Last Update Posted : October 31, 2016
|Condition or disease||Intervention/treatment|
|Gingivitis||Drug: Punica granatum Linn. Drug: chlorhexidine|
|Study Type :||Interventional (Clinical Trial)|
|Actual Enrollment :||35 participants|
|Intervention Model:||Parallel Assignment|
|Masking:||Double (Participant, Investigator)|
|Official Title:||Clinical Effectiveness and Microbiological Evaluation of a Mouthwash of Pomegranate (Punica Granatum Linn.) in School Children|
|Study Start Date :||March 2012|
|Primary Completion Date :||May 2012|
|Study Completion Date :||May 2012|
Experimental: Punica granatum Linn.
The childrens used the mouthwash contain pomegranate 6,25% twice daily for 14 days.
Drug: Punica granatum Linn.
Mouthwash (6,25% of Punica granatum Linn) 10mL per day during 14 days
Other Name: Pomegranate
Active Comparator: chlorhexidine
The childrens used the mouthwash contain chlorhexidine 0.12% twice daily for 14 days.
standard anti-bacterial mouthwash Mouthwash (0,12% chlorhexidine) 10mL per day during 14 days
Other Name: Periogard
- Difference in the Gingival Index scores. [ Time Frame: Baseline, Seventh Day and Fourteeth day (14 days) ]On day 0, we measured the Plaque Index (PI) (Silness; Löe, 1964) at baseline, on the seventh day and on the fourteenth day.
- Difference in the Gingival Bleeding Index scores. [ Time Frame: Baseline, Seventh Day andFourteeth day (14 days) ]On day 0, we measured the Bleeding on Probing Index (BPI) (Ainamo; Bay, 1975) at baseline, on the seventh day and on the fourteenth day.
- Difference in the Microbiological analysis of saliva for oral streptococcus count evolution from the start till the end of the study. [ Time Frame: Baseline and Fourteeth day (14 days) ]At baseline, we collected non-stimulated saliva samples into a sterile container for counting of oral streptococci in the laboratory. And on the fourteenth day, we carried out the second saliva collection and measured the clinical indices used.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT02949583
|Universidade Estadual Da Paraiba|
|Campina Grande, Paraiba, Brazil, 58.429-500|
|Principal Investigator:||DANÚBIA RM NÓBREGA, Mastering||Universidade Estadual da Paraiba|