Acute Dyspnea After Use of Non-invasive Ventilation in COPD and Emphysema (Deventilation Syndrome)
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|ClinicalTrials.gov Identifier: NCT02942134|
Recruitment Status : Unknown
Verified October 2016 by Felix JF Herth, Heidelberg University.
Recruitment status was: Not yet recruiting
First Posted : October 21, 2016
Last Update Posted : October 21, 2016
|Condition or disease|
|Obstructive Chronic Bronchitis|
Non-invasive ventilation (NIV) is a widespread therapy option for patients with hypercapnic failure due to COPD and emphysema. Augmented dyspnea after use of NIV is commonly found and leads not only to high patient discomfort, but can also be associated with acute respiratory failure. This monocentric obervation trial includes patients with COPD III°-IV° (GOLD) and emphysema and an established long term NIV therapy. During their routine inpatient follow-up, we will extend the routine examinations, focussing on the vulnerable first hour after the nocturnal use of NIV. This includes monitoring of breath rate, heart rate, pulsoxymetry, trancutaneous CO2, blood pressure and capillary blood gas analysis. Sonographic measurement of diaphragm movement and thickness will be complemented. Subjective dyspnea will be documented by use of the BORG scale.
By collecting this data, we hope to understand the pathomechanisms causing augmented dyspnea after NIV and thus provide information for therapeutical concepts to prevent it.
|Study Type :||Observational|
|Estimated Enrollment :||70 participants|
|Official Title:||Acquisition and Evaluation of Augemented Dyspnea After Use of Non-invasive Ventilation in Patients With COPD and Empysema (Deventilation Syndrome)|
|Study Start Date :||November 2016|
|Estimated Primary Completion Date :||October 2017|
|Estimated Study Completion Date :||May 2018|
- Incidence and severity of acute dyspnea after use of non-invasive Ventilation in COPD and emphysema [ Time Frame: May 2018 ]
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT02942134
|Contact: Mavi D Schellenberg, Dr.firstname.lastname@example.org|
|Contact: Felix FJ Herth, Prof.||email@example.com|
|Principal Investigator:||Felix FJ Herth, Prof.||Medical Director Thoraxklinik Heidelberg|