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Impact Evaluation of Urban Water Supply Improvements on Cholera and Other Diarrhoeal Diseases in Uvira, Democratic Republic of Congo

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ClinicalTrials.gov Identifier: NCT02928341
Recruitment Status : Recruiting
First Posted : October 10, 2016
Last Update Posted : July 25, 2019
Sponsor:
Information provided by (Responsible Party):
London School of Hygiene and Tropical Medicine

Study Description
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Brief Summary:
The aim of the study is to evaluate the impact of a large-scale urban water supply improvement intervention on cholera and other diarrhoeal diseases. The study uses a step wedge cluster randomised controlled trial (SWcRCT) to measure the effect of the intervention on cholera centre admission rates and confirmed cholera cases. A nested cohort study will examine changes in water-related practices following the intervention.

Condition or disease Intervention/treatment Phase
Cholera Diarrhea Other: Improved water supply Not Applicable

Study Design
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Study Type : Interventional  (Clinical Trial)
Estimated Enrollment : 5000 participants
Allocation: Randomized
Intervention Model: Factorial Assignment
Masking: None (Open Label)
Primary Purpose: Prevention
Official Title: Impact Evaluation of Urban Water Supply Improvements on Cholera and Other Diarrhoeal in Uvira, Democratic Republic of Congo
Actual Study Start Date : October 2016
Estimated Primary Completion Date : September 27, 2020
Estimated Study Completion Date : September 27, 2020

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Arms and Interventions
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Arm Intervention/treatment
No Intervention: No intervention
Current water supply access
Experimental: Intervention
Received water supply improvement intervention designed to improve access to tap water, consisting of community managed public taps, improved tap water distribution network, refurbished tap connections and promotion of new household tap connections.
 Other: Improved water supply


Outcome Measures
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Primary Outcome Measures :
  1. Admission rate to the Uvira Cholera Treatment Centre [ Time Frame: 36 months ]

Secondary Outcome Measures :
  1. Admission rate to the Uvira Cholera Treatment Centre of laboratory confirmed cholera cases [ Time Frame: 36 months ]

Eligibility Criteria
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Ages Eligible for Study:   Child, Adult, Older Adult
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Criteria

Inclusion Criteria:

  • Uvira resident admitted to the Uvira Cholera Treatment Centre in Uvira

Exclusion Criteria:

  • Any patients admitted during the period of intervention implementation in each cluster
Contacts and Locations
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To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT02928341


Contacts
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Contact: Karin Gallandat, PhD 00442076368636 karin.gallandat@lshtm.ac.uk

Locations
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Congo, The Democratic Republic of the
Centre de Traitement du Cholera, Hôpital General de Reference d'Uvira, Sud-Kivu, République Démocratique du Congo Recruiting
Uvira, Sud-Kivu, Congo, The Democratic Republic of the
Contact: Jaime Saidi    00243992023652    saidijaime2@outlook.com   
Sponsors and Collaborators
London School of Hygiene and Tropical Medicine
Investigators
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Principal Investigator: Oliver Cumming, MSc London School of Hygiene and Tropical Medicine
More Information
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Responsible Party: London School of Hygiene and Tropical Medicine
ClinicalTrials.gov Identifier: NCT02928341    
Other Study ID Numbers: 8913
First Posted: October 10, 2016    Key Record Dates
Last Update Posted: July 25, 2019
Last Verified: January 2019
Individual Participant Data (IPD) Sharing Statement:
Plan to Share IPD: No
Additional relevant MeSH terms:
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Cholera
Diarrhea
Signs and Symptoms, Digestive
Signs and Symptoms
 Vibrio Infections
Gram-Negative Bacterial Infections
Bacterial Infections