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The Acute Impact of Sit-stand Desks on Post-meal Blood Sugar Levels

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ClinicalTrials.gov Identifier: NCT02913079
Recruitment Status : Completed
First Posted : September 23, 2016
Last Update Posted : October 17, 2018
Sponsor:
Information provided by (Responsible Party):
Travis Saunders, University of Prince Edward Island

Brief Summary:
Context and Rationale: Uninterrupted sitting is associated with increased risk of diabetes, heart disease, and death, even among people who are physically active. These relationships are likely due to increases in post-meal blood sugar observed when people sit for long periods (e.g. > 1 hour) without interruption. In contrast to sitting, standing results in large reductions in post-meal blood sugar levels. Our group has recently shown that sit-stand desks result in large (e.g. 2.5 hour/day) reductions in occupational sitting time. Taken together, these findings suggest that sit-stand desks may help to reduce post-meal blood sugar levels. However, this has yet to be examined in the field. Theoretical Approach and Objectives: The objective of this randomized crossover study is to determine whether people have lower blood sugar when using a sit-stand desk, in comparison to a desk that can only be used while sitting. Methods and Procedures: Sixteen participants will be asked to wear a continuous glucose monitor to measure their blood sugar levels during 2 separate conditions. During one condition, they will be asked to use a sit-stand desk to sit and/or stand as much as they like during 1 workday. During the other condition, they will be asked to work at a seated desk for 1 workday. Participants will be provided with identical meals to eat during each of the two conditions. We hypothesize that participants will have lower blood sugar levels on the day when they use the sit-stand desk, in comparison to the day using a traditional seated desk. Significance and Future Use: If our results support this hypothesis, this would suggest that sit-stand desks may be a useful way to reduce blood sugar levels in people at risk for diabetes. This could also lead to larger population-based interventions studying the health impact of sit-stand desks.

Condition or disease Intervention/treatment Phase
Insulin Sensitivity Glucose Tolerance Sedentary Behaviour Physical Activity Behavioral: Sit-stand desk Behavioral: Sitting desk Not Applicable

Study Type : Interventional  (Clinical Trial)
Actual Enrollment : 14 participants
Allocation: Randomized
Intervention Model: Crossover Assignment
Masking: None (Open Label)
Primary Purpose: Basic Science
Official Title: The Acute Impact of Sit-stand Desks on Post-meal Blood Sugar Levels
Study Start Date : September 2016
Actual Primary Completion Date : June 2018
Actual Study Completion Date : September 2018

Resource links provided by the National Library of Medicine

MedlinePlus related topics: Blood Sugar

Arm Intervention/treatment
Experimental: Sit-stand desk
During this condition, participants will sit or stand as much as they like throughout a workday.
Behavioral: Sit-stand desk
Placebo Comparator: Sitting
During this condition, participants will work in the sitting position only.
Behavioral: Sitting desk



Primary Outcome Measures :
  1. Postprandial Glucose [ Time Frame: 12 hours ]
    Postprandial glucose will be assessed over 1 workday in both the experimental and control conditions.


Secondary Outcome Measures :
  1. Objectively measured minutes of light, moderate and vigorous physical activity. [ Time Frame: 24 hours ]
    Physical activity time will be assessed over 1 workday during both conditions.

  2. Objectively measured minutes of sitting [ Time Frame: 24 hours ]
    Sitting time will be assessed over 1 workday during both conditions.



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Ages Eligible for Study:   20 Years to 65 Years   (Adult, Older Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   Yes
Criteria

Inclusion Criteria:

  • To participate in this study, participants must be between the ages of 20 and 65, and have access to a sit-stand desk (depending on your workspace, we may be able to provide you with a sit-stand desk during the study if you do not already have one).

Exclusion Criteria:

  • Participants will be excluded if they are currently taking any diabetes medications targeting blood sugar or insulin sensitivity as this will impact our primary outcome of postprandial glucose. Participants will also be excluded if they are unable to stand or walk independently, as these are secondary outcomes in the present study.

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT02913079


Locations
Canada, Prince Edward Island
University of Prince Edward Island
Charlottetown, Prince Edward Island, Canada, C1A 4P3
Sponsors and Collaborators
University of Prince Edward Island

Responsible Party: Travis Saunders, Assistant Professor, University of Prince Edward Island
ClinicalTrials.gov Identifier: NCT02913079     History of Changes
Other Study ID Numbers: 6006774
First Posted: September 23, 2016    Key Record Dates
Last Update Posted: October 17, 2018
Last Verified: October 2018
Individual Participant Data (IPD) Sharing Statement:
Plan to Share IPD: No
Plan Description: No.

Additional relevant MeSH terms:
Insulin Resistance
Hyperinsulinism
Glucose Metabolism Disorders
Metabolic Diseases