Value of Radionuclide Cisternography (VERTICAL)
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|ClinicalTrials.gov Identifier: NCT02876614|
Recruitment Status : Completed
First Posted : August 24, 2016
Last Update Posted : August 24, 2016
Radionuclide cisternography (RC) is a nuclear medicine examination based on intrathecal injection of [111In]diethylenetriaminepentaacetic acid ([111In]DTPA). It is prescribed for two recommendations: detection of cerebrospinal fluid (CSF) leak/fistula and diagnosis of normal pressure hydrocephalus.
In the search part of CSF leak/fistula, RC offers the benefit of a 24-hour study of CSF unlike other reference tests.
In addition to SPECT/CT imaging, the radiopharmacist performs sampling in nasal cavities and throat of the patient to collect a possible flow of CSF.
These samples are analysed by radioactivity measurements and bring an added value to the exam.
The interest of this examination for management of CSF leak/fistula remains unclear.
The aim of this study is to identify and analyse results of all RC examinations performed since 2005 in the Nuclear Medicine department of the Neurological Hospital.
The full analysis of patients will allow discussing the role of RC in management of CSF leak/fistulae in clinical practice.
|Condition or disease|
|CSF Leak Fistula|
|Study Type :||Observational|
|Actual Enrollment :||113 participants|
|Official Title:||VALUE OF RADIONUCLIDE CISTERNOGRAPHY IN PATIENTS WITH CEREBROSPINAL FLUID LEAK|
|Study Start Date :||January 2005|
|Actual Primary Completion Date :||December 2005|
|Actual Study Completion Date :||December 2005|
- RC /SPECT/CT imaging [ Time Frame: one week ]Results of RC including results of SPECT/CT imaging and results of swabs counting (nasal cavities and throat or ear if applicable)
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT02876614
|Principal Investigator:||Elise LEVIGOUREUX, MD||Hospices Civils de Lyon|