Analysis of the Impact of the Fragility of the Over 70 Years of TIAprognosis (AIT70)
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|ClinicalTrials.gov Identifier: NCT02828488|
Recruitment Status : Active, not recruiting
First Posted : July 11, 2016
Last Update Posted : June 18, 2020
Fragility, geriatric concept recent identification is defined by simple physical indicators. The literature suggests that it is related to the risk of hospitalization, falls, institutionalization and death. Some studies have shown a link with heart disease, including heart failure. The link with the TIA (transient ischemic attack) has however never been studied. A fortiori, the impact of the fragility of the risk of recurrent stroke after TIA is unknown.
Several questions need to be asked: Among older patients hospitalized for TIA, what proportion of those completing the criteria of frailty? In this same population, is there a correlation between fragility and scores ABCD2 score itself predictive of the risk of subsequent ischemic stroke? In other words, fragile subjects who have a TIA Have a higher risk of ischemic stroke (which could cause a strengthening of prevention measures)?
|Condition or disease||Intervention/treatment|
|Vascular Stoke Ischemic Transient Ischemic Attack||Other: No intervention|
- Frailty is common among the elderly patient population who have a TIA. Compared to control groups of literature.
- Patients with high fragility score ABCD2 also have a high score.
- Patients with a high score of fragility also have a significant number of vascular risk factors (including atrial fibrillation)
- Patients with a high score of fragility also have an average length of stay (ALOS) higher than the others. So underlying the question is: can we learn to better identify patients who are going to need a bigger structure their output at home.
- Assess the feasibility of placing a fragile test in acute phase of AIT in USINV.
- To evaluate the frequency of frailty among the population of elderly patients who have a TIA.
- Compare in AIT over 70 years those with fragile high score to those with low scores, especially for ABCD2 score, vascular risk factors and the DMS.
o The fragility score:
- Choice of fragility score: among the fragility of scores, the most used in international literature is the score of Linda Fried. Moreover, the stress of the study is related to the environment of the USINV (shortly, short DMS, often tired patients). It is therefore important to use this study for a test only, but quick handover. The score Fried also has the advantage (J Gerontol A Biol Sci Med Sci 2001, 56 (3): M146-56) The first 4 items are simple clinical evaluation. The 5th (grip test) will be performed with a device (single gauge measuring the fingers bending strength) loan from the geriatric ward.
|Study Type :||Observational|
|Actual Enrollment :||110 participants|
|Official Title:||Analysis of the Impact of the Fragility of the Over 70 Years of TIA (Transient Ischemic Attack) Prognosis|
|Actual Study Start Date :||August 6, 2015|
|Actual Primary Completion Date :||June 30, 2019|
|Estimated Study Completion Date :||December 31, 2020|
- Other: No intervention
It is a descriptive study. No intervention
- Fried Score for fragility [ Time Frame: Day 1 ]
- ABCD Score [ Time Frame: Day 1 ]
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT02828488
|Groupe Hospitalier Paris Saint Joseph|
|Paris, Ile-de-France, France, 75014|
|Principal Investigator:||BRUANDET Marie, MD||Groupe Hospitalier Paris Saint Joseph|