Concomitant High-resolution Recording of Haemodynamic and Electrical Activities of Children With Typical or Atypical Absence Seizures (Absence)
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|ClinicalTrials.gov Identifier: NCT02819427|
Recruitment Status : Active, not recruiting
First Posted : June 30, 2016
Last Update Posted : August 21, 2018
This study, conducted in children with typical or atypical "absence" epilepsy, will consist of noninvasive recording of the metabolic activity of the brain concomitantly with electroencephalographic recording during seizures without the need for any additional examination. This examination will be performed by combining near-infrared spectroscopy (NIRS) optical imaging and Electroencephalography (EEG) in a simultaneous High-Resolution (HR) recording.
Surface electroencephalography (EEG) is a valuable tool to assess neuronal dysfunction from a functional point of view and is used in the routine follow-up of epileptic children. Optical imaging is a recent and promising medical imaging technique, which uses near-infrared light. This rapid, noninvasive and harmless quantitative technique can be easily used at the child's bedside or in the ward and provides metabolic information on brain functioning.
|Condition or disease||Intervention/treatment|
|Epilepsy||Device: Near Infra Red Spectroscopy (NIRS) Device: Electroencephalography (EEG)|
|Study Type :||Observational|
|Actual Enrollment :||10 participants|
|Official Title:||Concomitant High-resolution Recording of Haemodynamic and Electrical Activities of Children With Typical or Atypical Absence Seizures: Near-infrared Spectroscopy (NIRS) Coupled to Electroencephalography (EEG)|
|Study Start Date :||April 2013|
|Estimated Primary Completion Date :||August 2018|
|Estimated Study Completion Date :||August 2018|
children with absence epilepsy presenting either typical or atypical seizures
Device: Near Infra Red Spectroscopy (NIRS)
Device: Electroencephalography (EEG)
Electroencephalography (EEG) in a simultaneous High-Resolution (HR) recording.
- haemodynamic changes [ Time Frame: Day 0 ]haemodynamic changes by optical imaging, during the 4 interictal, preictal, ictal and postictal phases of absence seizures as defined by EEG analysis
To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.
Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT02819427
|Amiens, France, 80054|
|Principal Investigator:||Fabrice WALLOIS, MD, PhD||CHU Amiens|