Periodontal Inflammation and Immunity in Preclinical Rheumatoid Arthritis
The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government.
Read our disclaimer for details.
The purpose of this study is to evaluate the association of Rheumatoid Arthritis (RA)-related antibodies and periodontal inflammation in subjects at-risk for Rheumatoid Arthritis. Subjects will undergo periodontal and joint examinations, as well as collection of body fluids to measure Rheumatoid Arthritis-related antibodies.
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies.
Ages Eligible for Study:
18 Years to 99 Years (Adult, Senior)
Sexes Eligible for Study:
Accepts Healthy Volunteers:
The study population will include: subjects at-risk for RA, subjects with early RA, and healthy controls >40 years old.
Rheumatoid Arthritis-antibody positivity (anti-CCP) in the absence of arthritis or
Early RA <36 months since diagnosis
Antibiotic use prior to dental procedures or cleanings