Working...
ClinicalTrials.gov
ClinicalTrials.gov Menu
Trial record 1 of 221 for:    Recruiting, Not yet recruiting, Available Studies | Acute kidney injury
Previous Study | Return to List | Next Study

Clinical Values of Automated Electronic Alert for Acute Kidney Injury

The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Listing a study does not mean it has been evaluated by the U.S. Federal Government. Know the risks and potential benefits of clinical studies and talk to your health care provider before participating. Read our disclaimer for details.
ClinicalTrials.gov Identifier: NCT02793167
Recruitment Status : Recruiting
First Posted : June 8, 2016
Last Update Posted : January 7, 2019
Sponsor:
Information provided by (Responsible Party):
XinLing Liang, Guangdong General Hospital

Brief Summary:
Acute kidney injury (AKI) is common, serious and expensive.It is associated with significant mortality, morbidity and increased length of hospital stay.To improve clinical outcomes of AKI by early detection and timely referral to the renal,the investigators developed an electronic alert system which identifies all cases of AKI occurring in patients over 18 years.The system was also designed to collect data on AKI incidence one of the biggest tertiary hospital in China.

Condition or disease Intervention/treatment Phase
Acute Kidney Injury Device: AKI alert Not Applicable

Detailed Description:

A prospective, randomly controlled cohort study will be conducted agmong the patients with AKI who are detected by the use of AKI sniffer. The investigators chose to assess all inpatient serum creatinine results using a combination of "KDIGO" criteria.

The investigators randomly divided the patients into two groups:

  1. Usual care : patients will receive standard clinical care by the primary physicians
  2. AKI alert : an AKI alert will be sent to the the doctor in charge. Our team of kidney experts would give a suggestion if the the doctor in charge issue consultation applications.

Layout table for study information
Study Type : Interventional  (Clinical Trial)
Estimated Enrollment : 2000 participants
Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Single (Participant)
Primary Purpose: Diagnostic
Official Title: Clinical Values of Automated Electronic Alert for Acute Kidney injury-a Prospective ,Randomly Controlled Cohort Study
Study Start Date : March 2016
Estimated Primary Completion Date : December 2019
Estimated Study Completion Date : December 2019

Arm Intervention/treatment
No Intervention: Usual care
patients will receive standard clinical care by the doctor in charge.
Experimental: AKI alert
an AKI alert will send to the the doctor in charge.Our team of nephrologists would give suggestions if the doctor in charge issue consultation application.
Device: AKI alert



Primary Outcome Measures :
  1. Adverse events during hospitalization [ Time Frame: from start of AKI to discharge,up to 4 weeks ]
    cardiac shock/ need for intensive care/ cardiopulmonary resuscitation/ cardiac death/ death

  2. Incidence of cardiovascular disease and its occurrence time followed up for 1 years [ Time Frame: One year after discharge ]
    heart failure/ acute coronary syndrome/ readmission/cardiac readmission/ cardiovascular intervention or surgery

  3. The AKI outcome and its occurrence time followed up for 1 years [ Time Frame: One year after discharge ]
    AKI recovery/stop renal replacement therapy

  4. AKI recovery/stop renal replacement therapy [ Time Frame: from start of AKI to discharge,up to 4 weeks ]
    Glomerular filtration rate decreased/ new occurrence proteinuria/ original proteinuria aggravation


Secondary Outcome Measures :
  1. Proportion of nephrology referral [ Time Frame: from start of AKI to discharge,up to 4 weeks ]
  2. Diagnostic rate of AKI at discharge [ Time Frame: from start of AKI to discharge,up to 4 weeks ]
  3. Follow-up rate after discharge [ Time Frame: One year after discharge ]


Information from the National Library of Medicine

Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the contacts provided below. For general information, Learn About Clinical Studies.


Layout table for eligibility information
Ages Eligible for Study:   18 Years and older   (Adult, Older Adult)
Sexes Eligible for Study:   All
Accepts Healthy Volunteers:   No
Criteria

Inclusion Criteria:

  • adult patients with an Alert for AKI(based on KDIGO guidelines)

Exclusion Criteria:

  • patients already on dialysis for AKI at the time of alert
  • patients with End stage renal disease
  • patients <18 years of age
  • patients dissenting from participation according to the Ethics application

Information from the National Library of Medicine

To learn more about this study, you or your doctor may contact the study research staff using the contact information provided by the sponsor.

Please refer to this study by its ClinicalTrials.gov identifier (NCT number): NCT02793167


Contacts
Layout table for location contacts
Contact: Liang Xinling, MD,PhD 86-13808819770 xinlingliang@139.com

Locations
Layout table for location information
China, Guangdong
Nephrology Dept,Guangdong General Hospital Recruiting
Guangzhou, Guangdong, China
Contact: Liang Xinling, MD,PhD    86-13808819770    xinlingliang@139.com   
Sponsors and Collaborators
XinLing Liang

Layout table for additonal information
Responsible Party: XinLing Liang, Director of Blood Purification Center of Guangdong General Hospital, Guangdong General Hospital
ClinicalTrials.gov Identifier: NCT02793167     History of Changes
Other Study ID Numbers: GGH2016-1
First Posted: June 8, 2016    Key Record Dates
Last Update Posted: January 7, 2019
Last Verified: January 2019

Keywords provided by XinLing Liang, Guangdong General Hospital:
acute kidney injury
medication alert systems

Additional relevant MeSH terms:
Layout table for MeSH terms
Wounds and Injuries
Acute Kidney Injury
Renal Insufficiency
Kidney Diseases
Urologic Diseases